Demographic and clinical risk factors overall and by dialysis modality among patients with ESRD and stroke
| Variable | Level | Overall | Dialysis modality | ||||
| CRRT | IHD | OR | 95% CI | P value | |||
| Age at first stroke, mean (SD) | 69.0 (12.5) | 65.7 (13.0) | 69.3 (12.5) | 0.98 | 0.977 to 0.981 | <0.0001 | |
| Sex, n (%) | Female | 43,776 (49.9) | 2998 (48.0) | 40,778 (50.0) | 0.92 | 0.87 to 0.97 | 0.0016 |
| Male | 43,965 (50.1) | 3252 (52.0) | 40,713 (50.0) | 1.00 | |||
| Race, n (%) | Black | 27,750 (31.6) | 1519 (24.3) | 26,231 (32.2) | 0.67 | 0.63 to 0.71 | <0.0001 |
| Other | 4122 (4.7) | 281 (4.5) | 3841 (4.7) | 0.85 | 0.75 to 0.96 | ||
| White | 55,869 (63.7) | 4450 (71.2) | 51,419 (63.1) | 1.00 | |||
| Ethnicity, n (%) | Hispanic | 10,742 (12.2) | 560 (9.0) | 10,182 (12.5) | 0.69 | 0.63 to 0.75 | <0.0001 |
| Non-Hispanic | 76,999 (87.8) | 5690 (91.0) | 71,309 (87.5) | 1.00 | |||
| Essential hypertension, n (%) | Yes | 63,953 (72.9) | 4289 (68.6) | 59,664 (73.2) | 0.80 | 0.76 to 0.85 | <0.0001 |
| No | 23,788 (27.1) | 1961 (31.4) | 21,827 (26.8) | 1.00 | |||
| Diabetes, n (%) | Yes | 62,034 (70.7) | 4187 (67.0) | 57,847 (71.0) | 0.83 | 0.79 to 0.88 | <0.0001 |
| No | 25,707 (29.3) | 2063 (33.0) | 23,644 (29.0) | 1.00 | |||
| Tobacco, n (%) | Yes | 20,040 (22.8) | 1574 (25.2) | 18,466 (22.7) | 1.15 | 1.08 to 1.22 | <0.0001 |
| No | 67,701 (77.2) | 4676 (74.8) | 63,025 (77.3) | 1.00 | |||
| Atrial fibrillation, n (%) | Yes | 20,727 (23.6) | 1224 (19.6) | 19,503 (23.9) | 0.77 | 0.73 to 0.83 | <0.0001 |
| No | 67,014 (76.4) | 5026 (80.4) | 61,988 (76.1) | 1.00 | |||
| Hyperlipidemia, n (%) | Yes | 51,525 (58.7) | 3967 (63.5) | 47,558 (58.4) | 1.224 | 1.18 to 1.31 | <0.0001 |
| No | 36,216 (41.3) | 2283 (36.5) | 33,933 (41.6) | 1.00 | |||
CRRT, continuous renal replacement therapy; ESRD, end-stage renal disease; IHD, intermittent hemodialysis.