Demographic and biochemical parameters of subjects in the three groups
| Variables | CAD+OA (n=30) | CAD (n=30) | Ctrl (n=17) | P value |
| Age (years) | 56.13±1.4 | 53.13±1.7 | 49.88±1.9 | 0.028* |
| BMI (kg/m2) | 27.43±2.0 | 26.72±0.6 | 23.85±1.1 | 0.311 |
| FPG (mg/dL) | 99.00±4.8 | 98.96±3.7 | 105.9±4.5 | 0.222 |
| TG (mg/dL) | 130.82±14.9 | 120.5±8.9 | 128.8±11.6 | 0.759 |
| TC (mg/dL) | 141.00±6.9 | 152.66±5.8 | 180.05±9.6 | 0.003* |
| HDL-c (mg/dL) | 35.37±1.0 | 40.20±1.4 | 48.11±2.7 | <0.001* |
| LDL-c (mg/dL) | 79.62±6.0 | 88.36±4.9 | 106.69±7.8 | 0.009* |
| Sodium (mmol/L) | 138.14±0.4 | 137.51±0.4 | 138.71±0.9 | 0.338 |
| Potassium (mmol/L) | 4.15±0.0 | 4.08±0.0 | 4.06±0.1 | 0.746 |
| Cr (mg/dL) | 1.07±0.0 | 1.09±0.0 | 1.04±0.0 | 0.666 |
| Urea (mg/dL) | 33.59±1.9 | 34.34±1.3 | 34.91±2.8 | 0.906 |
| Hyperlipidemia (yes) | 21 (70) | 19 (63.33) | 7 (41.17) | 0.154 |
| Hypertension (yes) | 11 (36.66) | 16 (53.33) | 4 (23.52) | 0.205 |
Continuous and categorical variables are presented as mean±SEM and number (%), respectively.
*Significant difference was set at p<0.05.
BMI, body mass index; CAD, coronary artery disease; CAD+OA, coronary artery disease and opium addiction; Cr, creatinine; Ctrl, control; FPG, fasting plasma glucose; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides.