Table 2

Organochlorines (OCs) levels in patients with leukemia compared with healthy individuals

ALL
(n=72)		Control
(n=72)		P valueAML
(n=37)		Control
(n=37)		P value
OCs
(ng/mL)		LOD
(ng/mL)		Mean±SDMedian (min-max)Mean±SDMedian (min-max)Mean±SDMedian (min-max)Mean±SDMedian (min-max)
Alpha-HCH0.111.55±0.931.45
(0.1–3.13)		0.24±0.210.10
(0.1–0.92)		 <0.001* 1.56±0.951.52
(0.1–3.00)		0.26±0.240.14
(0.1–0.92)		 <0.001*
Beta-HCH0.140.65±0.390.52
(0.1–2.04)		0.20±0.190.10
(0.1–0.94)		 <0.001* 0.62±0.380.46
(0.3–2.04)		0.24±0.230.10
(0.1–0.94)		 <0.001*
Gamma-HCH0.190.72±0.610.51
(0.1–2.51)		0.15±0.100.10
(0.1–0.61)		 <0.001* 0.68±0.560.51
(0.1–2.26)		0.15±0.110.10
(0.1–0.61)		 <0.001*
2,4-DDE0.0292.15±1.172.89
(0.1–3.61)		0.28±0.250.10
(0.1–0.89)		 <0.001* 1.87±1.212.27
(0.1–3.38)		0.30±0.260.10
(0.1–0.89)		 <0.001*
4,4-DDE0.0380.70±0.660.48
(0.1–2.92)		0.12±0.060.10
(0.1–0.41)		 <0.001* 0.71±0.710.44
(0.1–2.92)		0.13±0.080.10
(0.01–0.41)		 <0.001*
2,4-DDT0.0430.58±0.570.46
(0.1–2.00)		0.21±0.180.10
(0.09–0.82)		 <0.001* 0.55±0.590.44
(0.1–2.00)		0.18±0.160.10
(0.1–0.82)		 <0.001*
4,4-DDT0.080.63±0.670.12
(0.1–1.80)		0.13±0.120.10
(0.1–0.95)		 <0.001* 0.60±0.660.10
(0.1–1.80)		0.13±0.140.10
(0.1–0.95)		 <0.001*

  • OCs levels were significantly higher in patients with leukemia than in healthy individuals (p<0.001). The results are stated as mean±SD, LOD, median, minimum, and maximum.

  • *P<0.05.

  • ALL, acute lymphoblastic leukemia; alpha-HCH, alpha-hexachlorocyclohexane; AML, acute myeloid leukemia; beta-HCH, beta-hexachlorocyclohexane; 2,4-DDE, 2,4-dichlorodiphenyldichloroethylene; 4,4-DDE, 4,4-dichlorodiphenyldichloroethylene; 2,4-DDT, 2,4-dichlorodiphenyltrichloroethane; 4,4-DDT, 4,4-dichlorodiphenyltrichloroethane; gamma-HCH, gamma-hexachlorocyclohexane; LOD, limit of detection.