Author and Year | Age of Patients (yrs) | Total | Antibiotic Name | Patients treated with antibiotics & developed HUS | Patient treated without antibiotics & developed HUS | Effect of Antibiotics (Success, Harm | P values |
---|---|---|---|---|---|---|---|
Ostroff, 1989 | <10 Subgroup | 75 | Erythromycin, ampicillin, and cotrimoxazole | 3/8 (38%) | 5/12 (22%) | No to minor Effect | p=0.07 |
Beth P. Bell, 1997 | <15 | 278 | TMP/SMZ, Ampicillin or Amoxicillin, Cephalosporin, Metronidazole | 8/50 (16%) | 28/128 (22%) | No Effect | p=0.56 |
Pavia, 1990 | <20 | 23 | Cotrimoxazole, sulfonamide | 5/8 (72%) | 0/7 (28%) | Harm | p<0.05 |
Smith KE, 2012 | <20 | 188 | Bactericidal antibiotics | 12/63 (19%) | 6/125 (5%) | Harm | p<0.01 |