Abstract 513 Table 1
HP (n=12)HC (n=12)
ParametersBaseline6 monthsp-valueBaseline6 monthsP-valuep* HP vs HC 6 months
Age (yr)43.1±1.341.1±1.8
Weight (lbs)248.8±12.2229.4±11.30.005236.6±6.8211±8.30.0080.07
Blood Pressure130/80±3/2116/72±3/30.006126/80±4/2113/73±4/20.0050.6
RMR1571±191862±180.0051569±171598±150.60.001
Irisin ( ng/ml)9.41±0.710.42±0.40.038.86±0.88.99±0.80.50.02
FGF-21 (pg/ml)166.39±41.36129.47±240.04114.25±30.48166.39±300.050.06
UCP-1 (ng/ml)0.30±0.060.33±0.070.050.82±0.350.62±0.260.030.04
p is significance of change from Baseline to 6 mo; p* is significance between HP vs HC at 6 mo.