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NASH and the risk of cirrhosis and hepatocellular carcinoma in type 2 diabetes

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Abstract

The risk of chronic liver disease and liver-related mortality is increased in patients with type 2 diabetes mellitus. Several cohort studies have suggested a metabolic pathway from nonalcoholic fatty liver, nonalcoholic steatohepatitis, cryptogenic cirrhosis, and eventually hepatocellular carcinoma. Although cardiovascular risk remains the major cause for excess mortality in type 2 diabetes mellitus, the risk of progressive liver disease should no longer be underscored.

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Correspondence to Elisabetta Bugianesi MD.

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Bugianesi, E., Vanni, E. & Marchesini, G. NASH and the risk of cirrhosis and hepatocellular carcinoma in type 2 diabetes. Curr Diab Rep 7, 175–180 (2007). https://doi.org/10.1007/s11892-007-0029-z

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