Prevention of thromboembolism after neurosurgery for brain and spinal tumors

South Med J. 2003 Jan;96(1):17-22. doi: 10.1097/01.SMJ.0000047628.44490.B2.

Abstract

Objective: Deep venous thrombosis (DVT) is a major cause of morbidity and mortality after surgery for primary and metastatic brain tumors.

Methods: We conducted a confidential survey of American neurosurgeons interested in tumor surgery to assess DVT risk awareness and thromboprophylaxis patterns.

Results: Of the 172 respondents, 108 (63%) underestimated the DVT risk after brain tumor surgery. After operating on patients who had brain or spinal tumors, 81.4 and 78.5% of respondents, respectively, reported using DVT prophylaxis. After performing brain tumor surgery, 76.2% of respondents reported using solely mechanical methods of prophylaxis "always" or "most of the time."

Conclusion: American neurosurgeons tend to underestimate the risk of DVT associated with brain tumor surgery and to use mechanical thromboprophylaxis despite the availability of effective pharmacologic antithrombotics. A better appreciation of the risk of thrombosis, combined with clinical studies to address safety, may enhance the use of prophylaxis and the perceived safety of antithrombotics in this setting.

MeSH terms

  • Anticoagulants / therapeutic use
  • Brain Neoplasms / surgery*
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Neurosurgery / methods*
  • Practice Patterns, Physicians'*
  • Risk Factors
  • Spinal Cord Neoplasms / surgery*
  • Surveys and Questionnaires
  • Thromboembolism / etiology
  • Thromboembolism / prevention & control*
  • United States

Substances

  • Anticoagulants