MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

Comput Biol Med. 1992 May;22(3):155-63. doi: 10.1016/0010-4825(92)90011-b.

Abstract

The pharmacokinetic software package MW/Pharm offers an interactive, user-friendly program which gives rapid answers in clinical practice. It comprises a database with pharmacokinetic parameters of 180 drugs, a medication history database, and procedures for an individual drug dosage regimen calculation. The included curve-fitting facilities allow estimation of pharmacokinetic parameters on the basis of medication history, taking into account a varying status of the patient with respect to body weight and kidney function, optionally using a Bayesian procedure. The module KinBes performs the evaluation of bioavailability studies, including various methods, and an extensive statistical evaluation of bioequivalence.

MeSH terms

  • Algorithms
  • Bayes Theorem
  • Biological Availability
  • Body Weight
  • Clinical Pharmacy Information Systems / standards*
  • Drug Monitoring*
  • Humans
  • Kidney / physiology
  • Mathematics
  • Medical History Taking
  • Pharmaceutical Preparations / administration & dosage*
  • Pharmacokinetics*
  • Software / standards*
  • Therapeutic Equivalency

Substances

  • Pharmaceutical Preparations