Abstract
Non-specific interstitial pneumonia (NSIP) belongs to the group of idiopathic interstitial pneumonias (IIP). However, NSIP can also be found in several other diseases. For example, the NSIP pattern is most commonly found in interstitial lung disease due to connective tissue disease. In this review, the definition and classification, aetiology, pathogenesis and histology, clinical symptoms, serological markers, lung function parameters, radiographic signs, treatment, and prognosis of NSIP are presented. Idiopathic NSIP as a distinct form of NSIP will be discussed separately.
© Georg Thieme Verlag KG Stuttgart · New York.
MeSH terms
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Adult
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Age Factors
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Anti-Inflammatory Agents / therapeutic use
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Autoantibodies / immunology
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Biopsy
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Child
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Collagen Diseases / classification
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Collagen Diseases / diagnosis
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Collagen Diseases / immunology
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Collagen Diseases / pathology
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Diagnosis, Differential
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Female
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Humans
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Image Enhancement
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Immunosuppressive Agents / therapeutic use
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Interferon-gamma / blood
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Interleukin-4 / blood
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Lung / pathology
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Lung Diseases, Interstitial / classification
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Lung Diseases, Interstitial / diagnosis*
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Lung Diseases, Interstitial / immunology
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Lung Diseases, Interstitial / pathology
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Male
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Middle Aged
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Prognosis
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Sex Factors
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Th1 Cells / immunology
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Th2 Cells / immunology
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Tomography, X-Ray Computed
Substances
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Anti-Inflammatory Agents
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Autoantibodies
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Immunosuppressive Agents
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Interleukin-4
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Interferon-gamma