Visceral fat volume predicts new-onset type 2 diabetes in patients with chronic hepatitis C

Motoh Iwasa; Rumi Mifuji-Moroka; Nagisa Hara; Masumi Ishidome; Kazuko Iwata; Ryosuke Sugimoto; Hideaki Tanaka; Naoki Fujita; Yoshinao Kobayashi; Yoshiyuki Takei

doi:10.1016/j.diabres.2011.09.016

Visceral fat volume predicts new-onset type 2 diabetes in patients with chronic hepatitis C

Diabetes Res Clin Pract. 2011 Dec;94(3):468-70. doi: 10.1016/j.diabres.2011.09.016. Epub 2011 Oct 19.

Authors

Motoh Iwasa¹, Rumi Mifuji-Moroka, Nagisa Hara, Masumi Ishidome, Kazuko Iwata, Ryosuke Sugimoto, Hideaki Tanaka, Naoki Fujita, Yoshinao Kobayashi, Yoshiyuki Takei

Affiliation

¹ Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan. motoh@clin.medic.mie-u.ac.jp

PMID: 22014765
DOI: 10.1016/j.diabres.2011.09.016

Abstract

Ninety seven patients with chronic hepatitis C (CHC) and 72 with non-alcoholic fatty liver disease (NAFLD) were enrolled. Increased visceral fat area (VFA) was associated with high values of HbA1c. The variables associated with a high risk of new-onset diabetes had a VFA>101 cm(2) in CHC, but not in NAFLD.

MeSH terms

Diabetes Mellitus, Type 2 / etiology*
Fatty Liver / complications*
Fatty Liver / pathology
Female
Glycated Hemoglobin / metabolism*
Hepacivirus / pathogenicity*
Hepatitis C, Chronic / complications*
Hepatitis C, Chronic / pathology
Hepatitis C, Chronic / virology
Humans
Insulin Resistance
Intra-Abdominal Fat / pathology*
Male
Middle Aged
Non-alcoholic Fatty Liver Disease
Risk Factors

Substances

Glycated Hemoglobin A
hemoglobin A1c protein, human