User profiles for Ardeschir-Hossein Ghofrani

Hossein Ardeschir Ghofrani

Justus-Liebig University Giessen, ECCPS, Kerckhoff-Klinik Bad Nauheim, Imperial College …
Verified email at innere.med.uni-giessen.de
Cited by 86616

New horizons in pulmonary arterial hypertension therapies

N Galiè, AH Ghofrani - European Respiratory Review, 2013 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a fatal disease associated with vasoconstriction
and vascular remodelling. There are three well-known pathways that contribute to the …

Identification of right heart-enriched genes in a murine model of chronic outflow tract obstruction

…, M Szibor, N Weissmann, AH Ghofrani… - Journal of molecular and …, 2010 - Elsevier
The right ventricle (RV) differs in several aspects from the left ventricle (LV) including its
embryonic origin, physiological role and anatomical design. In contrast to LV hypertrophy, little is …

Defining the clinical validity of genes reported to cause pulmonary arterial hypertension

…, M Eyries, MPE Subías, H Gall, S Ghio, AH Ghofrani… - Genetics in …, 2023 - Elsevier
Purpose Pulmonary arterial hypertension (PAH) is a rare, progressive vasculopathy with
significant cardiopulmonary morbidity and mortality. Genetic testing is currently recommended …

[HTML][HTML] Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration

S Pullamsetti, S Krick, H Yilmaz, AH Ghofrani… - Respiratory …, 2005 - Springer
Background The aim of the study was to assess the chronic effects of combined phosphodiesterase
3/4 inhibitor tolafentrine, administered by inhalation, during monocrotaline-induced …

[HTML][HTML] Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

RT Schermuly, C Inholte, AH Ghofrani, H Gall… - Respiratory …, 2005 - Springer
Inhaled prostanoids and phosphodiesterase (PDE) inhibitors have been suggested for
treatment of severe pulmonary hypertension. In catheterized rabbits with acute pulmonary …

Hypoxie-bedingte Hemmung der alveolären Flüssigkeitsresorption im Modell der isolierten, ventilierten und perfundierten Kaninchenlunge

KRG Grosse Kreymborg - 2009 - jlupub.ub.uni-giessen.de
… an dem verwendeten experimentellen Aufbau geht auf Ghofrani et al. zurück … Natrium- und
Wassertransportes, vormals beschrieben durch Ghofrani et al. , wird der Einfluss von Hypoxie …