Molecular genetics of the swine major histocompatibility complex, the SLA complex

JK Lunney, CS Ho, M Wysocki, DM Smith - Developmental & Comparative …, 2009 - Elsevier
The swine major histocompatibility complex (MHC) or swine leukocyte antigen (SLA) complex
is one of the most gene-dense regions in the swine genome. It consists of three major …

Importance of the major histocompatibility complex (swine leukocyte antigen) in swine health and biomedical research

SE Hammer, CS Ho, A Ando… - Annual review of …, 2020 - annualreviews.org
In pigs, the major histocompatibility complex (MHC), or swine leukocyte antigen (SLA)
complex, maps to Sus scrofa chromosome 7. It consists of three regions, the class I and class III …

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex

…, U Grimholt, J Kaufman, CS Ho… - Nucleic acids …, 2017 - academic.oup.com
The IPD-MHC Database project ( http://www.ebi.ac.uk/ipd/mhc/ ) collects and expertly curates
sequences of the major histocompatibility complex from non-human species and provides …

[HTML][HTML] A pool of eight virally vectored African swine fever antigens protect pigs against fatal disease

…, H Goldswain, GL Shimmon, Z Hargreaves, CS Ho… - Vaccines, 2020 - mdpi.com
Classical approaches to African swine fever virus (ASFV) vaccine development have not
been successful; inactivated virus does not provide protection and use of live attenuated …

[HTML][HTML] Identification and immunogenicity of African swine fever virus antigens

…, L Gault, R Nieto, V Norlin, C Gallardo, CS Ho… - Frontiers in …, 2019 - frontiersin.org
African swine fever (ASF) is a lethal haemorrhagic disease of domestic pigs for which there
is no vaccine. Strains of the virus with reduced virulence can provide protection against …

Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial …

…, JF Dawkins, M Kreke, K Cheng, D Luthringer, CS Ho… - Circulation, 2013 - Am Heart Assoc
Background— Magnetic resonance imaging (MRI) in the CArdiosphere-Derived aUtologous
stem CElls to reverse ventricUlar dySfunction (CADUCEUS) trial revealed that cardiosphere-…

Transplant of organs from donors with positive SARS‐CoV‐2 nucleic acid testing: A report from the organ procurement and transplantation network ad hoc disease …

…, C Fox, GJ Berry, KE Dunn, CS Ho… - Transplant Infectious …, 2023 - Wiley Online Library
Background Decisions to transplant organs from severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) nucleic acid test‐positive (NAT+) donors must balance risk of donor‐…

Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1

…, SH Ibrahim, KW Peng, CO Harding, CS Ho… - Science translational …, 2016 - science.org
We tested the hypothesis that ex vivo hepatocyte gene therapy can correct the metabolic
disorder in fumarylacetoacetate hydrolase–deficient (Fah −/− ) pigs, a large animal model of …

[HTML][HTML] Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac …

…, E Tseliou, K Cheng, DJ Luthringer, CS Ho… - PloS one, 2014 - journals.plos.org
Background Epicardial injection of heart-derived cell products is safe and effective post-myocardial
infarction (MI), but clinically-translatable transendocardial injection has never been …

Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs

…, T Yoshizumi, S Juhas, J Juhasova, CS Ho… - Science translational …, 2018 - science.org
The use of autologous (or syngeneic) cells derived from induced pluripotent stem cells (iPSCs)
holds great promise for future clinical use in a wide range of diseases and injuries. It is …