Purpose: Intestinal intussusception in adults is rare and the optimal management of this
problem remains controversial. The purpose of this study was to determine the causes of …

Purpose The purpose of this study was to compare the outcomes of patients treated with
chemoradiotherapy with a complete clinical response followed by either a “watch and wait” …

Abstract Development of colorectal cancer (CRC) involves sequential transformation of normal
mucosal tissues into benign adenomas and then adenomas into malignant tumors. The …

Purpose: This study is aimed at investigating the in vivo antitumor activity of a novel cell-impermeable
glucuronide prodrug, 9-aminocamptothecin glucuronide (9ACG), and elucidating …

Purpose Current medical treatments for slow transit constipation (STC) are often ineffective,
and total colectomy with ileorectal anastomosis has been the procedure of choice for …

Retinoid-inducible gene 1 (RIG1), also called tazarotene-induced gene 3, belongs to the
HREV107 gene family, which contains five members in humans. RIG1 is expressed in high …

Aim Uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) polymorphism plays a crucial
role in the increased susceptibility of patients to irinotecan and its toxicity. This study is a …

Background Colonic diverticular bleeding can usually be managed with conservative
treatment. However, in a selected group of patients under conditions of recurrent, persistent …

Retinoic acid receptor responder 1 (RARRES1) is a retinoid regulated gene. Its expression
is frequently down-regulated through DNA hypermethylation in several types of malignant …

Background Tazarotene-induced gene 1 (TIG1) is a retinoid-inducible type II tumour
suppressor gene. The B isoform of TIG1 (TIG1B) inhibits growth and invasion of cancer cells. …