Background It is well known that ventilation with high volume or pressure may damage
healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal …

Stanniocalcin-1 (STC1) is an endogenous glycoprotein whose anti-inflammatory effects occur
through induction of uncoupling proteins to reduce oxidative stress. In this study, we tested …

Background In Taiwan, lung cancers occur predominantly in never-smokers, of whom nearly
60% have stage IV disease at diagnosis. We aimed to assess the efficacy of low-dose CT (…

Aims: Obstructive sleep apnea (OSA) and insomnia commonly coexist; hypnotics are broadly
prescribed for insomnia therapy. However, the safety of hypnotics use in OSA patients is …

Background Axl is a cell surface receptor tyrosine kinase, and activation of the Axl attenuates
inflammation induced by various stimuli. Growth arrest-specific 6 (Gas6) has high affinity for …

We conducted a systematic review and meta-analysis to assess the clinical efficacy of high-flow
nasal cannula (HFNC) therapy as apneic oxygenation in critically ill patients who require …

Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) caused by
carbapenem-resistant Acinetobacter baumannii (CRAB) are both associated with significant …

Background and objective Tuberculosis (TB) and sarcoidosis are both granulomatous diseases
with potential interassociations. However, much uncertainty remains; thus, the present …

Bumetanide is a potent loop diuretic that acts as an inhibitor of sodium-potassium-chloride
cotransporter 2 (NKCC2) and its isoform NKCC1. Although the expression of NKCC2 is …

Nosocomial pneumonia caused by carbapenem-resistant gram-negative bacteria (CRGNB)
is a growing threat due to the limited therapeutic choices and high mortality rate. The aim of …