Background Deep learning offers considerable promise for medical diagnostics. We aimed
to evaluate the diagnostic accuracy of deep learning algorithms versus health-care …

Among the most noteworthy developments in ophthalmology over the last decade has been
the emergence of quantifiable high-resolution imaging modalities, which are typically non-…

Streptococcus pneumoniae is among the most significant causes of bacterial disease in
humans. Here we report the 2,038,615-bp genomic sequence of the gram-positive bacterium S. …

We report the structure, optical, and gas-sensing properties of ZnO nanorods with different
diameters. Vertically well-aligned homogeneous nanorods were grown along the c-axis …

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass
spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were …

Background More and more studies have shown that circular RNAs (circRNAs) play a critical
regulatory role in many cancers. However, the potential molecular mechanism of circRNAs …

Background Deep learning has the potential to transform health care; however, substantial
expertise is required to train such models. We sought to evaluate the utility of automated …

Background Patients with major depressive disorder (MDD) having active suicidal ideation
with intent require immediate treatment. Methods This double-blind study (ASPIRE II) …

Objective: To compare esketamine to placebo, each in addition to standard-of-care treatment,
for rapidly reducing major depressive disorder symptoms, including suicidal ideation. …

Excess O-glycosylation of proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) may be
involved in the pathogenesis of type 2 diabetes. The enzyme O-GlcNAc–selective N-acetyl-β-…