Inherited or acquired thrombophilias have been largely explored as a cause of pregnancy
complications. However, pathogenesis of obstetric complications, as fetal loss and …

In SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infected patients, hemostasis
shows an uncontrolled activation, with a high D-dimer concentration. 1, 2 It has been …

In a group of placentas from patients with preeclampsia or fetal growth restriction, reduced
annexin V gene expression in those carrying the M2 haplotype was observed. This is the first “…

Background: Endothelial dysfunction, coupled with inflammation, induces thrombo-inflammation.
In COVID-19, this process is believed to be associated with clinical severity. Von …

OBJECTIVE: Knowledge about risk factors for venous thromboembolism (VTE) is still limited.
A recently found haplotype within the natural anticoagulant protein annexin A5 (ANXA5) …

Pregnancies after assisted reproductive technologies (ART) have been associated with an
increased risk of venous thromboembolism (VTE). On the contrary, the magnitude of this risk …

Congenital Factor XI (FXI) deficiency shows a high variability in clinical phenotype. To date,
many allele variants have been shown to cause this bleeding disorder. However, the …

INTRODUCTION: Few studies have been carried out to investigate whether distinct areas of
full term placenta express different amounts of markers involved in the placental …

INTRODUCTION: Preeclampsia (PE) and fetal growth restriction (FGR) are multifactorial
diseases, whose pathogenesis is largely unknown. A significant relationship between …

Background Congenital fibrinogen disorders are caused by variants occurring within the
fibrinogen gene cluster. We describe ten subjects with disease-causative variants, adding …