STING promotes the growth of tumors characterized by low antigenicity via IDO activation
Cytosolic DNA sensing is an important process during the innate immune response that
activates the stimulator of interferon genes (STING) adaptor and induces IFN-I. STING incites …
activates the stimulator of interferon genes (STING) adaptor and induces IFN-I. STING incites …
[PDF][PDF] The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
Blockade of the inhibitory receptor TIM-3 shows efficacy in cancer immunotherapy clinical
trials. TIM-3 inhibits production of the chemokine CXCL9 by XCR1 + classical dendritic cells (…
trials. TIM-3 inhibits production of the chemokine CXCL9 by XCR1 + classical dendritic cells (…
[PDF][PDF] Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
Activation of unfolded protein responses (UPRs) in cancer cells undergoing endoplasmic
reticulum (ER) stress promotes survival. However, how UPR in tumor cells impacts anti-tumor …
reticulum (ER) stress promotes survival. However, how UPR in tumor cells impacts anti-tumor …
[PDF][PDF] The unfolded protein response mediator PERK governs myeloid cell-driven immunosuppression in tumors through inhibition of STING signaling
The primary mechanisms supporting immunoregulatory polarization of myeloid cells upon
infiltration into tumors remain largely unexplored. Elucidation of these signals could enable …
infiltration into tumors remain largely unexplored. Elucidation of these signals could enable …
Biodiesel production from one-step heterogeneous catalyzed process of Castor oil and Jatropha oil using novel sulphonated phenyl silane montmorillonite catalyst
…, GH Sayed, FZ Yehia, OI Habib, EA Mohamed - Journal of Molecular …, 2017 - Elsevier
The present study describes the preparation of novel modified montmorillonite clay in highly
acidic form and its evaluation as a heterogeneous catalyst in the production of biodiesel …
acidic form and its evaluation as a heterogeneous catalyst in the production of biodiesel …
Rutin and flavone analogs as prospective SARS-CoV-2 main protease inhibitors: In silico drug discovery study
MAA Ibrahim, EAR Mohamed… - Journal of Molecular …, 2021 - Elsevier
Coronavirus disease 2019 (COVID-19) is a new pandemic characterized by quick spreading
and illness of the respiratory system. To date, there is no specific therapy for Severe Acute …
and illness of the respiratory system. To date, there is no specific therapy for Severe Acute …
The inhibition performance of morpholinium derivatives on corrosion behavior of carbon steel in the acidized formation water: Theoretical, experimental and biocidal …
AA Farag, HE Abdallah, EA Badr, EA Mohamed… - Journal of Molecular …, 2021 - Elsevier
The aim of the present study is to synthesis and explore the inhibition influences of three
morpholinium cationic surfactants (coded: MCS-10, MCS-12, and MCS-14) on the carbon steel …
morpholinium cationic surfactants (coded: MCS-10, MCS-12, and MCS-14) on the carbon steel …
[HTML][HTML] ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Understanding the intrinsic mediators that render CD8 + T cells dysfunctional in the tumor
microenvironment is a requirement to develop more effective cancer immunotherapies. Here, …
microenvironment is a requirement to develop more effective cancer immunotherapies. Here, …
Experimental and theoretical assessment of benzopyran compounds as inhibitors to steel corrosion in aggressive acid solution
HE Hashem, AA Farag, EA Mohamed… - Journal of Molecular …, 2022 - Elsevier
The present work introduces an environmentally friendly synthesis of two heterocyclic α,β-unsaturated
carbonyl group benzopyran compounds (4-[(2E)-3-(1H-indol-3-yl)prop‑2-enoyl]-…
carbonyl group benzopyran compounds (4-[(2E)-3-(1H-indol-3-yl)prop‑2-enoyl]-…
New heterocyclic Schiff base‐metal complex: Synthesis, characterization, density functional theory study, and antimicrobial evaluation
HE Hashem, EA Mohamed, AA Farag… - Applied …, 2021 - Wiley Online Library
A new series of heterocyclic Schiff base complexes derived from the condensation of
nicotinohydrazide with different heterocyclic aldehyde, followed by metalation with Co (II) and Cu (II…
nicotinohydrazide with different heterocyclic aldehyde, followed by metalation with Co (II) and Cu (II…