2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) The …

…, L Mazzolai, N Meneveau, F Ní Áinle… - European heart …, 2020 - academic.oup.com
determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the individual …

Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right …

…, I Lang, G Meyer, F Ní Áinle… - European heart …, 2022 - academic.oup.com
This position paper provides a comprehensive guide for optimal follow-up of patients with
acute pulmonary embolism (PE), covering multiple relevant aspects of patient counselling. It …

Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid …

…, H Rahhal, M AlHamzah, LB Kreuziger, FN Áinle… - bmj, 2021 - bmj.com
Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin
among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised …

[HTML][HTML] An update on the global use of risk assessment models and thromboprophylaxis in hospitalized patients with medical illnesses from the world thrombosis day …

…, N Kucher, C McLintock, FN Áinle… - Journal of Thrombosis …, 2022 - Elsevier
Introduction Venous thromboembolism (VTE) is a leading cause of cardiovascular morbidity
and mortality. The majority of VTE events are hospital‐associated. In 2008, the …

[HTML][HTML] COVID-19 induces a hyperactive phenotype in circulating platelets

…, P Mallon, B McCullagh, N Moran, F Ní Áinle… - PLoS …, 2021 - journals.plos.org
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date. Although …

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an …

IM Bistervels, A Buchmüller, HMG Wiegers, FN Áinle… - The Lancet, 2022 - thelancet.com
Background Pregnancy-related venous thromboembolism is a leading cause of maternal
morbidity and mortality, and thromboprophylaxis is indicated in pregnant and post-partum …

Randomized trials of therapeutic heparin for COVID‐19: a meta‐analysis

…, L Baumann Kreuziger, F Ní Áinle… - … and practice in …, 2021 - Wiley Online Library
Background Pulmonary endothelial injury and microcirculatory thromboses likely contribute
to hypoxemic respiratory failure, the most common cause of death, in patients with COVID‐19…

Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the Highlow study, a randomised trial of two …

SM Bleker, A Buchmüller, C Chauleur, FN Áinle… - Thrombosis research, 2016 - Elsevier
Background Women with a history of venous thromboembolism (VTE) have a 2% to 10%
absolute risk of VTE recurrence during subsequent pregnancies. Therefore, current guidelines …

Platelet releasate proteome profiling reveals a core set of proteins with low variance between healthy adults

…, C Bennett, C McGuigan, C Gheveart, F Ní Áinle… - …, 2018 - Wiley Online Library
Upon activation, platelets release a powerful cocktail of soluble and vesicular signals,
collectively termed the "platelet releasate" (PR). Although several studies have used qualitative/…

Heparin for moderately ill patients with Covid-19

…, H Rahhal, M AlHamzah, LB Kreuziger, F Ní Áinle… - medRxiv, 2021 - medrxiv.org
Background Heparin, in addition to its anticoagulant properties, has anti-inflammatory and
potential anti-viral effects, and may improve endothelial function in patients with Covid-19. …