User profiles for Frits R Rosendaal

Frits Rosendaal

hoogleraar Klinische Epidemiologie, Leiden University Medical Center
Verified email at lumc.nl
Cited by 209214

Inherited thrombophilia: part 1

…, EK Ginter, JP Miletich, FR Rosendaal… - Thrombosis and …, 1996 - thieme-connect.com
Although familial clustering of venous thromboembolic events was observed at the start of
this century, it was not until the late nineteenseventies before our insight into the organization …

Oral contraceptives and the risk of venous thrombosis

…, BN Bouma, FR Rosendaal - … England Journal of …, 2001 - Mass Medical Soc
In the early 1960s, shortly after the introduction of oral contraceptives, the first case reports
appeared describing venous thrombosis and pulmonary emboli in women using this method …

Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis

BH Stegeman, M de Bastos, FR Rosendaal… - Bmj, 2013 - bmj.com
… Bernardine H Stegeman research associate13, Marcos de Bastos research fellow2, Frits
R Rosendaal professor of clinical epidemiology3, A van Hylckama Vlieg research fellow4, …

Mutation in blood coagulation factor V associated with resistance to activated protein C

RM Bertina, BPC Koeleman, T Koster, FR Rosendaal… - Nature, 1994 - nature.com
ACTIVATED protein C (APC) is a serine protease with potent anti-coagulant properties,
which is formed in blood on the endothelium from an inactive precursor 1 . During normal …

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous …

SR Poort, FR Rosendaal, PH Reitsma, RM Bertina - 1996 - ashpublications.org
We have examined the prothrombin gene as a candidate gene for venous thrombosis in
selected patients with a documented familial history of venous thrombophilia. All the exons and …

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

…, DJ Rader, LS Rallidis, C Rice, FR Rosendaal… - Nature …, 2011 - nature.com
We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …

Malignancies, prothrombotic mutations, and the risk of venous thrombosis

JW Blom, CJM Doggen, S Osanto, FR Rosendaal - Jama, 2005 - jamanetwork.com
ContextVenous thrombosis is a common complication in patients with cancer, leading to
additional morbidity and compromising quality of life.ObjectiveTo identify individuals with cancer …

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

T Koster, JP Vandenbroucke, FR Rosendaal… - The Lancet, 1993 - Elsevier
We undertook a population-based case-control study to test the clinical importance of a
hereditary abnormality in the coagulation system, characterised by poor anticoagulant response …

[HTML][HTML] Incidence and mortality of venous thrombosis: a population‐based study

…, SC Cannegieter, FR Rosendaal… - Journal of thrombosis …, 2007 - Elsevier
Background: Estimates of the incidence of venous thrombosis (VT) vary, and data on mortality
are limited. Objectives: We estimated the incidence and mortality of a first VT event in a …

The risk of myocardial infarction associated with antihypertensive drug therapies

…, TE Raghunathan, NS Weiss, FR Rosendaal… - Jama, 1995 - jamanetwork.com
Objective. —To assess the association between first myocardial infarction and the use of
antihypertensive agents. Design and Setting. —We conducted a population-based case-control …