User profiles for Geovanny F Perez
Geovanny F PerezAssociate Professor of Pediatric Pulmonology, Jacobs School of Medicine and Biomedical … Verified email at buffalo.edu Cited by 1013 |
Different next generation sequencing platforms produce different microbial profiles and diversity in cystic fibrosis sputum
Background Cystic fibrosis (CF) is an autosomal recessive disease characterized by recurrent
lung infections. Studies of the lung microbiome have shown an association between …
lung infections. Studies of the lung microbiome have shown an association between …
[HTML][HTML] Airway secretory microRNAome changes during rhinovirus infection in early childhood
Background Innate immune responses are fine-tuned by small noncoding RNA molecules
termed microRNAs (miRs) that modify gene expression in response to the environment. …
termed microRNAs (miRs) that modify gene expression in response to the environment. …
Rhinovirus infection in young children is associated with elevated airway TSLP levels
GF Perez, K Pancham, S Huseni… - European …, 2014 - Eur Respiratory Soc
Rhinovirus wheezing illnesses during early childhood are strongly linked with development
of asthma later in life [ 1]. Indeed, rhinovirus infection in the first 3 years of life is associated …
of asthma later in life [ 1]. Indeed, rhinovirus infection in the first 3 years of life is associated …
Rhinovirus‐induced airway cytokines and respiratory morbidity in severely premature children
GF Perez, K Pancham, S Huseni, A Jain… - Pediatric Allergy and …, 2015 - Wiley Online Library
Background Rhinovirus ( RV ) has been linked to the pathogenesis of asthma. Prematurity
is a risk factor for severe RV infection in early life, but is unknown if RV elicits enhanced pro‐…
is a risk factor for severe RV infection in early life, but is unknown if RV elicits enhanced pro‐…
[HTML][HTML] Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways
Background Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway
epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in …
epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in …
[PDF][PDF] Antibiotic multidrug resistance in the cystic fibrosis airway microbiome is associated with decreased diversity
Background Cystic fibrosis (CF) is associated with significant morbidity and early mortality
due to recurrent acute and chronic lung infections. The chronic use of multiple antibiotics …
due to recurrent acute and chronic lung infections. The chronic use of multiple antibiotics …
Innate IFN‐lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life
…, E Chorvinsky, K Abutaleb, GF Perez… - Clinical & …, 2020 - Wiley Online Library
Introduction IFN lambda (type III‐IFN‐λ1) is a molecule primarily produced by epithelial cells
that provides an important first‐line defence against viral respiratory infections and has …
that provides an important first‐line defence against viral respiratory infections and has …
[HTML][HTML] Characterization of cytomegalovirus lung infection in non-HIV infected children
…, CE Rodriguez-Martinez, GF Perez… - Viruses, 2014 - mdpi.com
Cytomegalovirus (CMV) is a prevalent pathogen in the immunocompromised host and invasive
pneumonia is a feared complication of the virus in this population. In this pediatric case …
pneumonia is a feared complication of the virus in this population. In this pediatric case …
Clinical definition of respiratory viral infections in young children and potential bronchiolitis misclassification
R Megalaa, GF Perez… - Journal of …, 2018 - journals.sagepub.com
Viral respiratory infections are often grouped as a single respiratory syndrome named ‘viral
bronchiolitis’, independently of the viral etiology or individual risk factors. Clinical trials and …
bronchiolitis’, independently of the viral etiology or individual risk factors. Clinical trials and …
[HTML][HTML] Airway mir-155 responses are associated with TH1 cytokine polarization in young children with viral respiratory infections
…, E Chorvinsky, X Xuchen, K Abutaleb, GF Perez… - PloS one, 2020 - journals.plos.org
Background MicroRNAs (miRs) control gene expression and the development of the
immune system and antiviral responses. MiR-155 is an evolutionarily-conserved molecule …
immune system and antiviral responses. MiR-155 is an evolutionarily-conserved molecule …