The diagnosis and assessment of pulmonary arterial hypertension is a rapidly evolving area,
with changes occurring in the definition of the disease, screening and diagnostic techniques…

Pulmonary arterial hypertension (PAH) is diagnosed by various investigations that are
essential for making the diagnosis, and by additional tests to clarify the category of pulmonary …

… Kovacs and H. Olschewski) independently screened the studies identified by the two
searches. Differences over inclusion of studies were resolved by consensus reached after …

Background Uncontrolled studies suggested that aerosolized iloprost, a stable analogue of
prostacyclin, causes selective pulmonary vasodilatation and improves hemodynamics and …

… Dr Olschewski has served on the advisory boards of Gilead and United Therapeutics; he
has received lecture fees from Gilead, Actelion, Bayer Schering, and Encysive; honoraria from …

… Olschewski H … Olschewski H … HA Ghofrani, H Olschewski, W Seeger, and F
Grimminger participated in analysis and interpretation of data, and revision of the report. …

Level of Evidence A Data derived from multiple randomised clinical trials or meta-analyses
Level of Evidence B Data derived from a single randomised clinical trial or large non-…

… Horst Olschewski … Horst Olschewski … Three patients who were on oxygen therapy 16
h/d before inclusion in this study kept the oxygen even through the training program. …

Background: Inhalation of the stable prostacyclin analogue iloprost is being studied for
treatment of pulmonary hypertension. The selective phosphodiesterase-5 inhibitor sildenafil has …

… Good compliance was defined as CPAP use for at least 5 h per night during 5 d of the
week. During the control night, the adequacy of the initially chosen CPAP was checked. It was …