A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells

WM Cao, K Murao, H Imachi, X Yu, H Abe, A Yamauchi… - Cancer research, 2004 - AACR
High-density lipoprotein (HDL) stimulates the growth of many types of cells, including those
of breast cancer. High levels of HDL are associated with an increased risk of breast cancer …

TNF-α stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells

K Murao, T Ohyama, H Imachi, T Ishida, WM Cao… - Biochemical and …, 2000 - Elsevier
MCP-1 is expressed in a variety of cell types including vascular endothelial cells following
induction by different stimuli such as tumor necrosis factor (TNF)-α. Although TNF-α stimulates …

Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen …

H Imachi, K Murao, H Dobashi, MM Bhuyan… - Breast cancer research …, 2010 - Springer
Multiple coactivator and corepressor complexes play an important role in endocrine processes
and breast cancer; in particular, estrogen and estrogen receptor-α (ERα) promote the …

Effects of sodium-glucose cotransporter 2 inhibitors on urinary excretion of intact and total angiotensinogen in patients with type 2 diabetes

…, H Kobori, M Miyakawa, H Imachi… - Journal of …, 2017 - journals.sagepub.com
We conducted a descriptive case study to examine the effects of sodium-glucose cotransporter
2 (SGLT2) inhibitors on urinary angiotensinogen excretion, which represents the function …

Expression of human scavenger receptor B1 on and in human platelets

H Imachi, K Murao, W Cao, S Tada… - … , and vascular biology, 2003 - Am Heart Assoc
Objective— The abundance of HDL particles correlates inversely with the incidence of coronary
heart disease. The human scavenger receptor B1 (hSR-B1/CLA-1) is a receptor for HDL. …

D-Psicose inhibits the expression of MCP-1 induced by high-glucose stimulation in HUVECs

K Murao, X Yu, WM Cao, H Imachi, K Chen, T Muraoka… - Life sciences, 2007 - Elsevier
Monocyte chemoattractant protein-1 (MCP-1) is a 76-amino-acid chemokine thought to be
the major chemotactic factor for monocytes. MCP-1 is found in macrophage-rich areas of …

[HTML][HTML] Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue

…, NH Rogers, MD Tara, JW Perfield, H Imachi… - Journal of lipid …, 2007 - ASBMB
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in
adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat …

[HTML][HTML] Combination therapy of ipilimumab and nivolumab induced thyroid storm in a patient with Hashimoto's disease and diabetes mellitus: a case report

K Yonezaki, T Kobayashi, H Imachi… - Journal of medical case …, 2018 - Springer
Background Recently, immune checkpoint inhibitors have widely been used for the
management of advanced melanoma. However, high-grade immune-related adverse events can …

Hyperglycemia suppresses hepatic scavenger receptor class B type I expression

K Murao, X Yu, H Imachi, WM Cao… - American Journal …, 2008 - journals.physiology.org
Hyperglycemia is a major risk factor for atherosclerotic disease. Hepatic scavenger receptor
class B type I (SR-BI) binds HDL particles that mediate reverse cholesterol transport and …

[HTML][HTML] Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells

K Murao, H Imachi, A Momoi, Y Sayo, H Hosokawa… - FEBS letters, 1999 - Elsevier
The chemokine monocyte chemoattractant protein-1 is a potent chemoattractant for monocytes.
Monocyte chemoattractant protein-1 is produced by vascular endothelial cells during …