Background: Gap junction remodeling is well established as a consistent feature of human
heart disease involving spontaneous ventricular arrhythmia. The mechanisms responsible for …

The use of catheter-based irreversible electroporation in clinical cardiac laboratories,
termed pulsed-field ablation (PFA), is gaining international momentum among cardiac …

Circ Heart Fail. 2018; 11: e005425. DOI: 10.1161/CIRCHEARTFAILURE. 118.005425 October
2018 2 functional benefit, which may be because of (1) lack of structural support, and (2) …

Heart failure (HF) post-myocardial infarction (MI) presents with increased vulnerability to
monomorphic ventricular tachycardia (mmVT). To appropriately evaluate new therapies for …

In swine models, there are well-established protocols for creating a closed-chest myocardial
infarction (MI) as well as protocols for characterization of cardiac function with cardiac …

Background. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
are under preclinical investigation as a cell-based therapy for heart failure post-myocardial …

Although radiofrequency ablation has revolutionized the management of tachyarrhythmias,
the rate of arrhythmia recurrence is a large drawback. Successful substrate identification is …

Background: The therapeutic use of irreversible electroporation in clinical cardiac laboratories,
termed pulsed field ablation (PFA), is gaining pre-regulatory approval momentum among …

This review will outline cell-based therapy for heart failure focusing on tissue engineering to
deliver cells to the damaged heart. We will present an overview of the central approaches …

Patients diagnosed with heart failure with reduced ejection fraction (HFrEF) are at increased
risk of monomorphic ventricular tachycardia (VT) and ventricular fibrillation. The presence of …