User profiles for Javad Alizadeh
Javad AlizadehDepartment of Human Anatomy and Cell Science, College of Medicine, University of … Verified email at myumanitoba.ca Cited by 15022 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
…, M Ali, MA Alim Al-Bari, S Aliwaini, J Alizadeh… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered the …
Since then, this topic has received increasing attention, and many scientists have entered the …
A novel electrochemical epinine sensor using amplified CuO nanoparticles and an-hexyl-3-methylimidazolium hexafluorophosphate electrode
…, I Sheikhshoaie, M Ranjbar, J Alizadeh… - New Journal of …, 2019 - pubs.rsc.org
This study suggests a carbon paste electrode modified with CuO nanoparticles and n-hexyl-3-methylimidazolium
hexafluorophosphate (CPE/CuO-NPs/HMIPF6) as a powerful tool for …
hexafluorophosphate (CPE/CuO-NPs/HMIPF6) as a powerful tool for …
[HTML][HTML] Cellular commitment in the developing cerebellum
The mammalian cerebellum is located in the posterior cranial fossa and is critical for motor
coordination and non-motor functions including cognitive and emotional processes. The …
coordination and non-motor functions including cognitive and emotional processes. The …
The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
P Mehrbod, SR Ande, J Alizadeh, S Rahimizadeh… - Virulence, 2019 - Taylor & Francis
Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
[HTML][HTML] Pleiotropic effects of statins: A focus on cancer
The statin drugs (‘statins’) potently inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA)
reductase by competitively blocking the active site of the enzyme. Statins decrease de novo …
reductase by competitively blocking the active site of the enzyme. Statins decrease de novo …
New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets
Colorectal cancer (CRC), despite numerous therapeutic and screening attempts, still remains
a major life-threatening malignancy. CRC etiology entails both genetic and environmental …
a major life-threatening malignancy. CRC etiology entails both genetic and environmental …
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts
…, A Samali, J Patterson, J Alizadeh… - … of Physiology-Lung …, 2018 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease in adults with limited treatment
options. Autophagy and the unfolded protein response (UPR), fundamental processes …
options. Autophagy and the unfolded protein response (UPR), fundamental processes …
[HTML][HTML] Mevalonate cascade inhibition by simvastatin induces the intrinsic apoptosis pathway via depletion of isoprenoids in tumor cells
The mevalonate (MEV) cascade is responsible for cholesterol biosynthesis and the
formation of the intermediate metabolites geranylgeranylpyrophosphate (GGPP) and …
formation of the intermediate metabolites geranylgeranylpyrophosphate (GGPP) and …
Simvastatin increases temozolomide‐induced cell death by targeting the fusion of autophagosomes and lysosomes
Temozolomide (TMZ) is a chemotherapy agent used to treat Grade IV astrocytoma, also
known as glioblastoma (GBM). TMZ treatment causes DNA damage that results in tumor cell …
known as glioblastoma (GBM). TMZ treatment causes DNA damage that results in tumor cell …
[HTML][HTML] Autophagy, apoptosis, the unfolded protein response, and lung function in idiopathic pulmonary fibrosis
Autophagy, apoptosis, and the unfolded protein response (UPR) are fundamental biological
processes essential for manifold cellular functions in health and disease. Idiopathic …
processes essential for manifold cellular functions in health and disease. Idiopathic …