Mevalonate pathway antagonist suppresses formation of serous tubal intraepithelial carcinoma and ovarian carcinoma in mouse models

…, H Kashima, RC Wu, JG Jung, JC Kuan… - Clinical Cancer …, 2015 - AACR
Purpose: Statins are among the most frequently prescribed drugs because of their efficacy
and low toxicity in treating hypercholesterolemia. Recently, statins have been reported to …

Turmeric improves post-prandial working memory in pre-diabetes independent of insulin

…, YC Chou, WH Fang, JT Lee, JC Kuan… - Asia Pacific journal …, 2014 - search.informit.org
Background and Objectives: Cognitive impairment develops with pre-diabetes and dementia
is a complication of diabetes. Natural products like turmeric and cinnamon may ameliorate …

Elevated uric acid level as a significant predictor of chronic kidney disease: a cohort study with repeated measurements

YC Chou, JC Kuan, T Yang, WY Chou, PC Hsieh… - Journal of …, 2015 - Springer
Background Cohort studies evaluating increased serum uric acid (SUA) level as a chronic
kidney disease (CKD) risk factor have yielded variable results. We aimed to assess the …

[HTML][HTML] DNA methylation combinations in adjacent normal colon tissue predict cancer recurrence: evidence from a clinical cohort study

JC Kuan, CC Wu, CA Sun, CM Chu, FG Lin, CH Hsu… - PLoS …, 2015 - journals.plos.org
Accumulating evidence has suggested the requirement for further stratification of patients in
the same tumor stage according to molecular factors. We evaluate the combination of cancer …

Predictive value of serum apolipoprotein B/apolipoprotein AI ratio in metabolic syndrome risk: a Chinese cohort study

YC Chou, JC Kuan, CH Bai, T Yang, WY Chou… - Endocrine, 2015 - Springer
The purpose of this study was to evaluate whether the apolipoprotein B/apolipoprotein AI (apoB/apoA-I)
ratio is a promising risk predictor of metabolic syndrome (MetS) and to …

Clinical stage and risk of recurrence and mortality: interaction of DNA methylation factors in patients with colorectal cancer

…, T Yang, YM Tsai, JC Kuan… - Journal of …, 2016 - journals.sagepub.com
Aberrant DNA methylation plays a crucial role in cancer development; however, prospective
evidence of an interaction between molecular biomarkers and cancer staging for predicting …

[HTML][HTML] Predicting the progress of colon cancer by DNA methylation markers of the p16 gene in feces-Evidence from an animal model

WC Wu, CH Hsu, JC Kuan, JF Hsieh… - … and molecular biology, 2013 - SciELO Brasil
A new noninvasive screening tool for colorectal neoplasia detects epigenetic alterations
exhibited by gastrointestinal tumor cells shed into stool. There is insufficient existing data to …

[PDF][PDF] Molecular detection of human bocavirus 1 and 2 in children with acute gastroenteritis in Taiwan

MB Tang, CM Chu, YC Chou, JC Kuan… - Southeast Asian Journal …, 2015 - thaiscience.info
Human bocaviruses (HBoVs) have been detected in human gastrointestinal infections
worldwide. Although HBoV global prevalence and strains diversity have been reported, but …

A study of the frequency of methylation of gene promoter regions in colorectal cancer in the Taiwanese population

CC Wu, JC Kuan, CH Hsu, TA Chen, CA Sun, T Yang… - Journal of genetics, 2013 - Springer
Transcriptional silencing of tumour-suppressor genes by hypermethylation of promoter-region
CpG islands is an important pathway results in tumourigenesis development (Esteller 2007…

[HTML][HTML] Long-term predictive models of risk factors for early chronic kidney disease: a longitudinal study

WC Wu, PC Hsieh, FK Hu, JC Kuan, CM Chu, CA Sun… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background The high incidence and prevalence of chronic kidney disease (CKD) in Taiwan
have produced tremendous burdens on health care resources. The work environment of air …