User profiles for Jinping Lai

Jinping Lai

Penn State University; Rutgers University; Xiamen University
Verified email at rci.rutgers.edu
Cited by 1400

[HTML][HTML] Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer

J Lai, J Chien, J Staub, R Avula, EL Greene… - Journal of Biological …, 2003 - ASBMB
Emerging data suggest that signaling by heparin-binding growth factors is influenced by the
sulfation state of N-acetylglucosamine residues of heparan sulfate proteoglycans (HSPGs). …

Role of vitamin E for nonalcoholic steatohepatitis in patients with type 2 diabetes: a randomized controlled trial

…, R Lomonaco, SK Subbarayan, J Lai… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE While vitamin E has shown to improve nonalcoholic steatohepatitis (NASH) in
patients without diabetes, information on patients with type 2 diabetes mellitus (T2DM) is …

Versatile fluorescence resonance energy transfer-based mesoporous silica nanoparticles for real-time monitoring of drug release

J Lai, BP Shah, E Garfunkel, KB Lee - ACS nano, 2013 - ACS Publications
We describe the development of a versatile fluorescence resonance energy transfer (FRET)-based
real-time monitoring system, consisting of (a) coumarin-labeled-cysteine tethered …

Real-time monitoring of ATP-responsive drug release using mesoporous-silica-coated multicolor upconversion nanoparticles

J Lai, BP Shah, Y Zhang, L Yang, KB Lee - ACS nano, 2015 - ACS Publications
Stimuli-responsive drug delivery vehicles have garnered immense interest in recent years
due to unparalleled progress made in material science and nanomedicine. However, the …

Diagnostic accuracy of noninvasive fibrosis models to detect change in fibrosis stage

…, D Carpenter, J Freebersyser, D King, J Lai… - Clinical …, 2019 - Elsevier
Background & Aims Noninvasive methods are needed to determine disease stage in patients
with nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic performance of …

Familial adenomatous polyposis syndrome: an update and review of extraintestinal manifestations

…, NR Evans, NJ Phillips, J Lai… - … of pathology & …, 2019 - meridian.allenpress.com
Context.— Familial adenomatous polyposis (FAP) is a rare genetic disorder with autosomal
dominant inheritance, defined by numerous adenomatous polyps, which inevitably progress …

An upconversion nanoparticle with orthogonal emissions using dual NIR excitations for controlled two‐way photoswitching

J Lai, Y Zhang, N Pasquale… - Angewandte Chemie …, 2014 - Wiley Online Library
Developing multicolor upconversion nanoparticles (UCNPs) with the capability of regulating
their emission wavelengths in the UV to visible range in response to external stimuli can …

[PDF][PDF] Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma

JP Lai, DS Sandhu, C Yu, T Han, CD Moser… - …, 2008 - Wiley Online Library
It has been shown that the heparin‐degrading endosulfatase, sulfatase 1 (SULF1), functions
as a liver tumor suppressor, but the role of the related sulfatase, sulfatase 2 (SULF2), in liver …

Performance of plasma biomarkers and diagnostic panels for nonalcoholic steatohepatitis and advanced fibrosis in patients with type 2 diabetes

…, C Soldevilla-Pico, RJ Firpi-Morell, J Lai… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE The 2019 Standards of Medical Care in Diabetes suggested that patients with
nonalcoholic fatty liver disease (NAFLD) should be evaluated for liver fibrosis. However, the …

Anti-CD20 antibody promotes cancer escape via enrichment of tumor-evoked regulatory B cells expressing low levels of CD20 and CD137L

M Bodogai, C Lee Chang, K Wejksza, J Lai, M Merino… - Cancer research, 2013 - AACR
The possible therapeutic benefits of B-cell depletion in combating tumoral immune escape
have been debated. In support of this concept, metastasis of highly aggressive 4T1 breast …