Lipoprotein ratios: physiological significance and clinical usefulness in cardiovascular prevention

…, P González-Santos, JF Ascaso… - Vascular health and …, 2009 - Taylor & Francis
Low-density lipoprotein (LDL) cholesterol concentration has been the prime index of
cardiovascular disease risk and the main target for therapy. However, several lipoprotein ratios or “…

Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism

JF Ascaso, S Pardo, JT Real, RI Lorente… - Diabetes …, 2003 - Am Diabetes Assoc
OBJECTIVE—To identify a reliable yet simple indirect method for detection of insulin
resistance (IR). RESEARCH DESIGN AND METHODS—A total of 65 subjects (44 men and 21 …

Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population

JF Ascaso, P Romero, JT Real, RI Lorente… - European journal of …, 2003 - Elsevier
Background: Our objective was to investigate the relationship between abdominal obesity (AO),
as measured by waist circumference (WC), insulin resistance (IR), and components of …

Gastroesophageal reflux in diabetes mellitus

I Lluch, JF Ascaso, F Mora, M Minguez… - Official journal of the …, 1999 - journals.lww.com
OBJECTIVE: Although abnormal gastroesophageal (GE) reflux is the most frequent alteration
of the gastrointestinal tract, its prevalence in diabetes mellitus (DM) is not widely known. …

[HTML][HTML] Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study

…, R Cooper, G Sanz, JM Castellano, JF Ascaso… - PLoS …, 2017 - journals.plos.org
Introduction The potential impact of targeting different components of an adverse lipid profile
in populations with multiple cardiovascular risk factors is not completely clear. This study …

[HTML][HTML] The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype

…, S Martínez-Hervás, JT Real, JF Ascaso… - Diabetologia, 2017 - Springer
Aims/hypothesis Recent clinical studies indicate that glucagon-like peptide-1 (GLP-1)
analogues prevent acute cardiovascular events in type 2 diabetes mellitus but their mechanisms …

[PDF][PDF] Cocientes lipoproteicos: significado fisiológico y utilidad clínica de los índices aterogénicos en prevención cardiovascular

…, PG Santos, JF Ascaso… - Clínica e …, 2010 - … .farmacoterapia-sanidadmadrid.org
La estimación del riesgo cardiovascular se ha convertido en la piedra angular de las guías
clínicas de prevención cardiovascular. Si bien la aterosclerosis es multifactorial en su origen, …

Homozygous familial hypercholesterolemia in Spain: prevalence and phenotype–genotype relationship

…, JT Real, F Blanco-Vaca, JF Ascaso… - Circulation …, 2016 - Am Heart Assoc
Background— Homozygous familial hypercholesterolemia (HoFH) is a rare disease
characterized by elevated plasma levels of low-density lipoprotein cholesterol (LDL-C) and …

Insulin resistance aggravates atherosclerosis by reducing vascular smooth muscle cell survival and increasing CX3CL1/CX3CR1 axis

…, L Piqueras, JT Real, JF Ascaso… - Cardiovascular …, 2014 - academic.oup.com
Aims Insulin resistance (IR) is a major risk factor for cardiovascular disease and atherosclerosis.
Life-threatening acute events are mainly due to rupture of unstable plaques, and the …

Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis

…, NY Wu-Xiong, J Ortega, M Civera, JF Ascaso… - International journal of …, 2018 - nature.com
f SAT and VAT sections were incubated with. mouse anti-human CXCL10 antibody or. mouse
anti-human CXCL11 antibody and immunoreactivity was visualized using … Juan F Ascaso