Identification of a novel, human multilymphoid progenitor in cord blood
QL Hao, J Zhu, MA Price, KJ Payne… - Blood, The Journal …, 2001 - ashpublications.org
The earliest stages of lymphoid commitment from human pluripotent hematopoietic stem
cells have not been defined. A clonogenic subpopulation of CD34 + CD38 − cord blood cells …
cells have not been defined. A clonogenic subpopulation of CD34 + CD38 − cord blood cells …
Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen
…, KP Garrett, LF Thompson, MID Rossi, KJ Payne… - Nature …, 2001 - nature.com
Estrogen is a negative regulator of lymphopoiesis and provides an experimental tool for
probing relationships between lymphocyte precursors and stem cells. We found that expression …
probing relationships between lymphocyte precursors and stem cells. We found that expression …
Human papillomavirus type 16 E6* induces oxidative stress and DNA damage
High-risk types of human papillomavirus (HPV) are the causative agents of virtually all cases
of cervical cancer and a significant proportion of other anogenital cancers, as well as both …
of cervical cancer and a significant proportion of other anogenital cancers, as well as both …
IL-7 Dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow
…, MA Price, NR Wall, S Dovat, KJ Payne - The Journal of …, 2009 - journals.aai.org
IL-7 is critical for B cell production in adult mice; however, its role in human B lymphopoiesis
is controversial. One challenge was the inability to differentiate human cord blood (CB) or …
is controversial. One challenge was the inability to differentiate human cord blood (CB) or …
[HTML][HTML] Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
…, S Glasgow, AW Aruni, J Unternaehrer, KJ Payne… - PloS one, 2017 - journals.plos.org
Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory
responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular …
responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular …
[HTML][HTML] Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors
…, DJ Baylink, A Neises, JB Kiroyan, X Meng, KJ Payne… - PloS one, 2013 - journals.plos.org
The ability to efficiently generate integration-free induced pluripotent stem cells (iPSCs)
from the most readily available source—peripheral blood—has the potential to expedite the …
from the most readily available source—peripheral blood—has the potential to expedite the …
[HTML][HTML] Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1
…, Z Gurel, T Ronni, C Song, KY Hung, KJ Payne… - Journal of Biological …, 2009 - ASBMB
Ikaros encodes a zinc finger protein that is involved in gene regulation and chromatin
remodeling. The majority of Ikaros localizes at pericentromeric heterochromatin (PC-HC) where it …
remodeling. The majority of Ikaros localizes at pericentromeric heterochromatin (PC-HC) where it …
Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia
…, H Schjerven, M Muschen, KJ Payne… - Blood, The Journal …, 2015 - ashpublications.org
Ikaros (IKZF1) is a tumor suppressor that binds DNA and regulates expression of its target
genes. The mechanism of Ikaros activity as a tumor suppressor and the regulation of Ikaros …
genes. The mechanism of Ikaros activity as a tumor suppressor and the regulation of Ikaros …
[HTML][HTML] Efficient reprogramming of human cord blood CD34+ cells into induced pluripotent stem cells with OCT4 and SOX2 alone
…, RJ Su, KJ Payne, L Ritter, DS Gridley, J Wang… - Molecular Therapy, 2012 - cell.com
The reprogramming of cord blood (CB) cells into induced pluripotent stem cells (iPSCs) has
potential applications in regenerative medicine by converting CB banks into iPSC banks for …
potential applications in regenerative medicine by converting CB banks into iPSC banks for …
Residency and activation of myeloid cells during remodeling of the prepartum murine cervix
KJ Payne, LA Clyde, AJ Weldon, TA Milford… - Biology of …, 2012 - academic.oup.com
Remodeling of the cervix is a critical early component of parturition and resembles an
inflammatory process. Infiltration and activation of myeloid immune cells along with production of …
inflammatory process. Infiltration and activation of myeloid immune cells along with production of …