[HTML][HTML] Characterization of CLA-1, a human homologue of rodent scavenger receptor BI, as a receptor for high density lipoprotein and apoptotic thymocytes

K Murao, V Terpstra, SR Green, N Kondratenko… - Journal of Biological …, 1997 - ASBMB
Recently, a murine scavenger receptor type B class I (SR-BI) was identified that binds high
density lipoprotein (HDL) and mediates the selective uptake of cholesterol esters. The human …

The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In Vivo

…, H Mori, T Himoto, K Okano, Y Suzuki, K Murao… - Molecular cancer …, 2012 - AACR
Recent studies suggest that metformin, which is commonly used as an oral anti-hyperglycemic
agent of the biguanide family, may reduce cancer risk and improve prognosis, but the …

Rare sugar D-psicose improves insulin sensitivity and glucose tolerance in type 2 diabetes Otsuka Long-Evans Tokushima Fatty (OLETF) rats

…, K Kamitori, Y Dong, Y Hirata, K Murao… - Biochemical and …, 2011 - Elsevier
A rare sugar, d-psicose has progressively been evaluated as a unique metabolic regulator of
glucose and lipid metabolism, and thus represents a promising compound for the treatment …

A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells

WM Cao, K Murao, H Imachi, X Yu, H Abe, A Yamauchi… - Cancer research, 2004 - AACR
High-density lipoprotein (HDL) stimulates the growth of many types of cells, including those
of breast cancer. High levels of HDL are associated with an increased risk of breast cancer …

[HTML][HTML] Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo

…, K Okano, Y Suzuki, K Murao… - International …, 2014 - spandidos-publications.com
Metformin is a commonly used oral anti-hyperglycemic agent of the biguanide family. Recent
studies suggest that metformin may reduce cancer risk and improve prognosis. However, …

TNF-α stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells

K Murao, T Ohyama, H Imachi, T Ishida, WM Cao… - Biochemical and …, 2000 - Elsevier
MCP-1 is expressed in a variety of cell types including vascular endothelial cells following
induction by different stimuli such as tumor necrosis factor (TNF)-α. Although TNF-α stimulates …

[HTML][HTML] Chronic restraint stress inhibits hair growth via substance P mediated by reactive oxygen species in mice

…, GQ Wang, XP Zhou, Y Jiang, J Shang, K Murao… - PloS one, 2013 - journals.plos.org
Backgrounds Solid evidence has demonstrated that psychoemotional stress induced alteration
of hair cycle through neuropeptide substance P (SP) mediated immune response, the …

[HTML][HTML] Effects of glucose and insulin on rat apolipoprotein AI gene expression

K Murao, Y Wada, T Nakamura, AH Taylor… - Journal of Biological …, 1998 - ASBMB
We have examined the regulation of apolipoprotein AI (apoA-I) gene expression in response
to glucose and insulin. In Hep G2 cells, endogenous apoA-I mRNA was suppressed by one-…

[HTML][HTML] Metformin suppresses expression of the selenoprotein P gene via an AMP-activated kinase (AMPK)/FoxO3a pathway in H4IIEC3 hepatocytes

…, H Iwama, K Chikamoto, Y Saito, K Murao… - Journal of Biological …, 2014 - ASBMB
Selenoprotein P (SeP; encoded by SEPP1 in humans) is a liver-derived secretory protein
that induces insulin resistance in type 2 diabetes. Suppression of SeP might provide a novel …

Association of serum anti-periodontal pathogen antibody with ischemic stroke

…, K Matsuo, K Deguchi, H Masugata, K Murao… - Cerebrovascular …, 2012 - karger.com
Background: Periodontitis increases the risk of atherosclerotic cardiovascular disease and
ischemic stroke. In this study, we evaluated whether serum antibody levels against individual …