[HTML][HTML] Cell-penetrating peptides in diagnosis and treatment of human diseases: from preclinical research to clinical application

J Xie, Y Bi, H Zhang, S Dong, L Teng, RJ Lee… - Frontiers in …, 2020 - frontiersin.org
Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have
been predominantly used in basic and preclinical research during the last 30 years. Since …

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

…, W Lu, K Yun, AS Lee, W Jiang, L Teng… - Nature biomedical …, 2020 - nature.com
Exosomes are attractive as nucleic-acid carriers because of their favourable pharmacokinetic
and immunological properties and their ability to penetrate physiological barriers that are …

[HTML][HTML] Synthesis and biological application of polylactic acid

G Li, M Zhao, F Xu, B Yang, X Li, X Meng, L Teng… - Molecules, 2020 - mdpi.com
Over the past few decades, with the development of science and technology, the field of
biomedicine has rapidly developed, especially with respect to biomedical materials. Low toxicity …

[HTML][HTML] Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

J Yang, D Dai, X Zhang, L Teng, L Ma, YW Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cancer remains a severe threat to human health. To date, although various therapeutic
methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT), …

[HTML][HTML] Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

…, Y Wang, WJ Lu, E Bahrani, LJ Lee, L Teng… - Nature biomedical …, 2023 - nature.com
The success of messenger RNA therapeutics largely depends on the availability of delivery
systems that enable the safe, effective and stable translation of genetic material into …

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

…, Z Chen, A Zhang, B Yu, RJ Lee, L Teng… - Journal of Controlled …, 2016 - Elsevier
Exosomes, the smallest subgroup of extracellular vesicles, have been recognized as
extracellular organelles that contain genetic and proteomic information for long distance …

Nanotechnology for the delivery of phytochemicals in cancer therapy

J Xie, Z Yang, C Zhou, J Zhu, RJ Lee, L Teng - Biotechnology advances, 2016 - Elsevier
The aim of this review is to summarize advances that have been made in the delivery of
phytochemicals for cancer therapy by the use of nanotechnology. Over recent decades, much …

[HTML][HTML] Exosomes as smart drug delivery vehicles for cancer immunotherapy

…, S Wang, M Sun, Y Cui, J Xing, L Teng… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer immunotherapy
owing to their good biocompatibility, low toxicity, and low immunogenicity. Some Exos-…

Cabazitaxel-loaded human serum albumin nanoparticles as a therapeutic agent against prostate cancer

…, J Lu, Q Meng, L Teng, D Wang, L Teng - International Journal …, 2016 - Taylor & Francis
Cabazitaxel-loaded human serum albumin nanoparticles (Cbz-NPs) were synthesized to
overcome vehicle-related toxicity of current clinical formulation of the drug based on Tween-80 (…

Advances in multiple stimuli-responsive drug-delivery systems for cancer therapy

R Jia, L Teng, L Gao, T Su, L Fu, Z Qiu… - International journal of …, 2021 - Taylor & Francis
Nanomedicines afford unique advantages in therapeutic intervention against tumors. However,
conventional nanomedicines have failed to achieve the desired effect against cancers …