User profiles for Leszek Kaczmarek
 | Leszek KaczmarekNencki Institute, Warsaw, Poland Verified email at nencki.edu.pl Cited by 21460 |
[HTML][HTML] MMPs in learning and memory and neuropsychiatric disorders
Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
The involvement of the anterior cingulate cortex in remote contextual fear memory
Although the molecular, cellular, and systems mechanisms required for initial memory
processing have been intensively investigated, those underlying permanent memory storage …
processing have been intensively investigated, those underlying permanent memory storage …
Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory
Matrix metalloproteinases (MMPs) are extracellular proteases that have well recognized roles
in cell signaling and remodeling in many tissues. In the brain, their activation and function …
in cell signaling and remodeling in many tissues. In the brain, their activation and function …
A gene for neuronal plasticity in the mammalian brain: Zif268/Egr-1/NGFI-A/Krox-24/TIS8/ZENK?
E Knapska, L Kaczmarek - Progress in neurobiology, 2004 - Elsevier
Zif268 is a transcription regulatory protein, the product of an immediate early gene. Zif268
was originally described as inducible in cell cultures; however, it was later shown to be …
was originally described as inducible in cell cultures; however, it was later shown to be …
Post‐stroke depression: mechanisms, translation and therapy
The interaction between depression and stroke is highly complex. Post‐stroke depression (
PSD ) is among the most frequent neuropsychiatric consequences of stroke. Depression also …
PSD ) is among the most frequent neuropsychiatric consequences of stroke. Depression also …
Matrix metalloproteinase-9 undergoes expression and activation during dendritic remodeling in adult hippocampus
Neurons of adult brain are able to remodel their synaptic connections in response to various
stimuli. Modifications of the peridendritic environment, including the extracellular matrix, are …
stimuli. Modifications of the peridendritic environment, including the extracellular matrix, are …
MicroRNA loss enhances learning and memory in mice
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role
in a modulation of translation of mRNA transcripts necessary for differentiation in many cell …
in a modulation of translation of mRNA transcripts necessary for differentiation in many cell …
MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
…, A Salamian, L Kaczmarek - Journal of …, 2016 - Wiley Online Library
Matrix metalloproteinase‐9 ( MMP ‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
Important role of matrix metalloproteinase 9 in epileptogenesis
…, W Zuschratter, OP Ottersen, L Kaczmarek - The Journal of cell …, 2008 - rupress.org
Temporal lobe epilepsy (TLE) is a devastating disease in which aberrant synaptic plasticity
plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic enzyme …
plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic enzyme …
[HTML][HTML] Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain
J Dzwonek, M Rylski, L Kaczmarek - FEBS letters, 2004 - Elsevier
More than 20 matrix metalloproteinases (MMPs) and four of their endogenous tissue
inhibitors (TIMPs) act together to control tightly temporally restricted, focal proteolysis of …
inhibitors (TIMPs) act together to control tightly temporally restricted, focal proteolysis of …