[HTML][HTML] Targeting cancer stem cell pathways for cancer therapy
L Yang, P Shi, G Zhao, J Xu, W Peng, J Zhang… - Signal transduction and …, 2020 - nature.com
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources
L Yang, LM Zhang - Carbohydrate polymers, 2009 - Elsevier
Some polysaccharides isolated from natural sources show various important biological
activities, such as antitumor, immunomodulatory, and anti-inflammatory effects, which are …
activities, such as antitumor, immunomodulatory, and anti-inflammatory effects, which are …
Early expression and cellular localization of proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α in human traumatic spinal cord injury
L Yang, PC Blumbergs, NR Jones, J Manavis… - Spine, 2004 - journals.lww.com
Study Design. Post-traumatic inflammatory response was studied in 11 human cases of acute
spinal cord contusion injury. Objectives. To examine the inflammatory cellular response …
spinal cord contusion injury. Objectives. To examine the inflammatory cellular response …
[PDF][PDF] The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation
Increased activation of the serine-glycine biosynthetic pathway is an integral part of cancer
metabolism that drives macromolecule synthesis needed for cell proliferation. Whether this …
metabolism that drives macromolecule synthesis needed for cell proliferation. Whether this …
Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat
L Yang, NR Jones, PC Blumbergs… - Journal of clinical …, 2005 - Elsevier
The post-traumatic inflammatory response in acute spinal cord contusion injury was studied
in the rat. Mild and severe spinal cord injury (SCI) was produced by dropping a 10 g weight …
in the rat. Mild and severe spinal cord injury (SCI) was produced by dropping a 10 g weight …
Amphiphilic cholesteryl grafted sodium alginate derivative: Synthesis and self-assembly in aqueous solution
L Yang, B Zhang, L Wen, Q Liang, LM Zhang - Carbohydrate Polymers, 2007 - Elsevier
A novel water soluble amphiphilic sodium alginate derivative grafted with 3 cholesteryl
groups per 100 hexuronic acid residues (CSAD-3) has been first synthesized with N,N′-…
groups per 100 hexuronic acid residues (CSAD-3) has been first synthesized with N,N′-…
[PDF][PDF] KDM4C and ATF4 cooperate in transcriptional control of amino acid metabolism
The histone lysine demethylase KDM4C is often overexpressed in cancers primarily through
gene amplification. The molecular mechanisms of KDM4C action in tumorigenesis are not …
gene amplification. The molecular mechanisms of KDM4C action in tumorigenesis are not …
Improving arc joining of Al to steel and Al to stainless steel
H Dong, L Yang, C Dong, S Kou - Materials Science and Engineering: A, 2012 - Elsevier
Gas-tungsten arc welding (GTAW) with controlled heat input could avoid the formation of
massive brittle Al–Fe intermetallics during solidification in dissimilar-metal joining of aluminum …
massive brittle Al–Fe intermetallics during solidification in dissimilar-metal joining of aluminum …
Bispecific aptamer chimeras enable targeted protein degradation on cell membranes
The ability to regulate membrane protein abundance offers great opportunities for developing
therapeutic sites for various diseases. Herein, we describe a platform for the targeted …
therapeutic sites for various diseases. Herein, we describe a platform for the targeted …
pH-Responsive charge switchable PEGylated ε-poly-l-lysine polymeric nanoparticles-assisted combination therapy for improving breast cancer treatment
Z Guo, J Sui, M Ma, J Hu, Y Sun, L Yang, Y Fan… - Journal of controlled …, 2020 - Elsevier
Stimuli-responsive nanotechnology-mediated drug co-delivery system is a notable strategy
to improve access of the systemically administered chemotherapeutics to the tumors. Herein, …
to improve access of the systemically administered chemotherapeutics to the tumors. Herein, …