The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp

F Guerrero-Romero, LE Simental-Mendía… - The Journal of …, 2010 - academic.oup.com
Context: To meet the worldwide challenge of emerging diabetes, accessible and inexpensive
tests to identify insulin resistance are needed. Objective: To evaluate the sensitivity and …

The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects

LE Simental-Mendía, M Rodríguez-Morán… - … syndrome and related …, 2008 - liebertpub.com
Background: Because the insulin test is expensive and is not available in most laboratories
in the cities of undeveloped countries, we tested whether the product of fasting triglycerides …

[HTML][HTML] Obesity and inflammation: epidemiology, risk factors, and markers of inflammation

…, LE Simental-Mendía… - International journal of …, 2013 - hindawi.com
Obesity is a public health problem that has reached epidemic proportions with an increasing
worldwide prevalence. The global emergence of obesity increases the risk of developing …

Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial

…, N Khalili, E Naimi, LE Simental-Mendía… - Biomedicine & …, 2016 - Elsevier
Background Cytokines are involved in the development of metabolic abnormalities that may
result in metabolic syndrome (MetS). Since curcumin has shown anti-inflammatory properties…

Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials

A Sahebkar, AFG Cicero, LE Simental-Mendía… - Pharmacological …, 2016 - Elsevier
Background Tumor necrosis factor-α (TNF-α) is a key inflammatory mediator and its reduction
is a therapeutic target in several inflammatory diseases. Curcumin, a bioactive polyphenol …

[HTML][HTML] Efficacy and safety of phytosomal curcumin in non-alcoholic fatty liver disease: a randomized controlled trial

…, R Mohtashami, R Jafari, LE Simental-Mendía… - Drug …, 2017 - thieme-connect.com
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease characterized by excess
lipid deposition in the hepatic tissue and subsequent oxidative and inflammatory damage. …

Curcumin lowers serum lipids and uric acid in subjects with nonalcoholic fatty liver disease: a randomized controlled trial

…, R Jafari, LE Simental-Mendía… - Journal of …, 2016 - journals.lww.com
Background: Nonalcoholic fatty liver disease (NAFLD) is one of the most common hepatic
diseases in the general adult population. Dyslipidemia, hyperuricemia, and insulin resistance …

Effects of curcuminoids plus piperine on glycemic, hepatic and inflammatory biomarkers in patients with type 2 diabetes mellitus: a randomized double-blind placebo …

…, E Sahebi, S Namazi, LE Simental-Mendía… - Drug …, 2018 - thieme-connect.com
Introduction Curcuminoids have been shown to reduce glycemia and related complications
in diabetes. In the present study, we evaluated the impact of curcuminoids plus piperine …

Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials

G Derosa, P Maffioli, LE Simental-Mendía, S Bo… - Pharmacological …, 2016 - Elsevier
The aim of this meta-analysis was to evaluate the efficacy of curcuminoids supplementation
on circulating concentrations of IL-6 in randomized controlled trials (RCTs). The search …

Fasting triglycerides and glucose index as a diagnostic test for insulin resistance in young adults

…, JR Jiménez-Flores, LE Simental-Mendia… - Archives of medical …, 2016 - Elsevier
Background and Aims Although the Glucose and Triglyceride levels (TyG) index is useful for
identification of insulin resistance (IR) in different ethnic groups, it has not been evaluated in …