Background The use of transcatheter aortic-valve replacement has been shown to reduce
mortality among high-risk patients with aortic stenosis who are not candidates for surgical …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted as the document was compiled through …

Background Previous trials have shown that among high-risk patients with aortic stenosis,
survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical …

The focus of the “2014 AHA/ACC Guideline for the Management of Patients With Valvular
Heart Disease” 9, 10 (2014 VHD guideline) was the diagnosis and management of adult …

Background Among patients with aortic stenosis who are at intermediate or high risk for
death with surgery, major outcomes are similar with transcatheter aortic-valve replacement (…

Background Percutaneous coronary intervention (PCI) involving drug-eluting stents is
increasingly used to treat complex coronary artery disease, although coronary-artery bypass …

Objectives : The aim of the current Valve Academic Research Consortium (VARC)-2 initiative
was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI) …

Background Among patients with heart failure who have mitral regurgitation due to left ventricular
dysfunction, the prognosis is poor. Transcatheter mitral-valve repair may improve their …

… This report is dedicated to the memory of Michael J Davidson, MD, our cherished colleague
and friend, for his outstanding contributions to the PARTNER trial and for his inspirational …

Aims The Valve Academic Research Consortium (VARC), founded in 2010, was intended to
(i) identify appropriate clinical endpoints and (ii) standardize definitions of these endpoints …