User profiles for Morten Hedetoft
Morten HedetoftResearch Fellow at Department of Anaesthesia, Centre of Head and Orthopedics … Verified email at regionh.dk Cited by 459 |
[HTML][HTML] Adjunctive hyperbaric oxygen treatment for necrotising soft-tissue infections: A systematic review and meta-analysis
M Hedetoft, MH Bennett… - Diving and Hyperbaric …, 2021 - ncbi.nlm.nih.gov
Methods The review was prospectively registered (PROSPERO; CRD42020148706).
MEDLINE, EMBASE, CENTRAL and CINAHL were searched for eligible studies that reported …
MEDLINE, EMBASE, CENTRAL and CINAHL were searched for eligible studies that reported …
Evaluation of endothelial function by peripheral arterial tonometry and relation with the nitric oxide pathway
M Hedetoft, NV Olsen - Nitric Oxide, 2014 - Elsevier
Endothelial dysfunction is an important component in the development of cardiovascular
diseases. Endothelial function may be evaluated by peripheral arterial tonometry (PAT) which …
diseases. Endothelial function may be evaluated by peripheral arterial tonometry (PAT) which …
Patient's characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study
…, Y Karlsson, MB Hansen, P Polzik, M Hedetoft… - Intensive care …, 2019 - Springer
Purpose Necrotising soft-tissue infections (NSTI) are characterised by necrosis, fast progression,
and high rates of morbidity and mortality, but our knowledge is primarily derived from …
and high rates of morbidity and mortality, but our knowledge is primarily derived from …
Incidence, comorbidity and mortality in patients with necrotising soft-tissue infections, 2005–2018: a Danish nationwide register-based cohort study
M Hedetoft, MB Madsen, LB Madsen, O Hyldegaard - BMJ open, 2020 - bmjopen.bmj.com
Objective To assess the incidence, comorbidities, treatment modalities and mortality in patients
with necrotising soft-tissue infections (NSTIs) in Denmark. Design Nationwide population-…
with necrotising soft-tissue infections (NSTIs) in Denmark. Design Nationwide population-…
Hyperbaric oxygen treatment is associated with a decrease in cytokine levels in patients with necrotizing soft‐tissue infection
M Hedetoft, P Garred, MB Madsen… - Physiological …, 2021 - Wiley Online Library
Background The pathophysiological understanding of the inflammatory response in necrotizing
soft‐tissue infection (NSTI) and its impact on clinical progression and outcomes are not …
soft‐tissue infection (NSTI) and its impact on clinical progression and outcomes are not …
Hyperbaric oxygen therapy
O Hyldegaard, M Hedetoft - Ugeskrift for laeger, 2020 - europepmc.org
Hypoxia triggers hypoxia-inducible factor (HIF). Not only hypoxia triggers downstream HIF
target genes for transcription, as intermittent hyperoxia also possesses similar capabilities, …
target genes for transcription, as intermittent hyperoxia also possesses similar capabilities, …
[HTML][HTML] SuPAR correlates with mortality and clinical severity in patients with necrotizing soft-tissue infections: results from a prospective, observational cohort study
…, J Tavenier, MB Madsen, O Andersen, M Hedetoft… - Scientific Reports, 2019 - nature.com
Necrotizing soft tissue infections (NSTI) have a 90-day mortality rate of 18–22%. Tools are
needed for estimating the prognosis and severity of NSTI upon admission. We evaluated …
needed for estimating the prognosis and severity of NSTI upon admission. We evaluated …
[HTML][HTML] Key pathways and genes that are altered during treatment with hyperbaric oxygen in patients with sepsis due to necrotizing soft tissue infection (HBOmic study …
Background For decades, the basic treatment strategies of necrotizing soft tissue infections (NSTI)
have remained unchanged, primarily relying on aggressive surgical removal of …
have remained unchanged, primarily relying on aggressive surgical removal of …
Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection
Necrotizing soft-tissue infection (NSTI) is a rare, severe, and fast-progressing bacterial
infection associated with a high risk of developing sepsis or septic shock. Increasing evidence …
infection associated with a high risk of developing sepsis or septic shock. Increasing evidence …
Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection
The inflammatory response in patients with necrotizing soft-tissue infection (NSTI) is excessive
and often causes collateral damage, thereby worsening disease severity and prognosis. …
and often causes collateral damage, thereby worsening disease severity and prognosis. …