The emergence of the novel SARS coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), has resulted in an unprecedented pandemic that has …

… NOS enzymes catalyze the production of nitric oxide from N-arginine; superoxide can react
with nitric oxide producing peroxynitrite which is highly reactive oxidizing DNA, proteins, and …

Doxorubicin (Dox), a widely used chemotherapy drug, can also cause cardiotoxic effects
leading to heart failure. The excessive oxidative stress caused by Dox results in the …

… and left ventricular hypertrophy (n=15), those with more prominent obesity and diabetes (n=13),
and a group that mixed both features (mixed; n=17) as previously described. …

… After 48 h, cells were transfected (50 MOI) with adenovirus expressing GFP-LC3 and after 20
h 100 n… Navid Koleini is supported by an Alfred Deacon doctoral scholarship and a Bank of …

Iron plays an important role in mammalian physiological processes. It is a critical
component for the function of many proteins, including enzymes that require heme and iron-sulfur …

… in favor of using atrial tissue for these initial studies is that, unlike human ventricular tissue,
it was possible for us to obtain a relatively large number of small tissue fragments (n = 60) …

Objective To evaluate the effect of metformin treatment on the risperidone-induced body
weight gain in patients. Methods In a 12-weeks, double-blind, placebo controlled, randomized …

… A total of n = 30 sham-operated and n = 49 LAD-ligated animals were used to acquire the …
measurements represented in panel A (n = 3 untreated controls; n = 6 biological replicates per …

MTORC1 integrates signaling from the immune microenvironment to regulate T cell activation,
differentiation, and function. TSC2 in the tuberous sclerosis complex tightly regulates …