Background and objective: Previous studies have indicated a high incidence of lung cancer
in IPF, and some have identified its risk factors. However, those studies were retrospective …

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) catalyzes the rate-limiting step of
tryptophan (Trp) degradation along the kynurenine (Kyn) pathway. By depleting tryptophan, IDO …

BACKGROUND: Acute exacerbation (AE) is currently established as a distinct condition
with acute deterioration of respiratory status in idiopathic pulmonary fibrosis (IPF). Recently, …

Background Interstitial lung disease (ILD) is a common manifestation of polymyositis (PM),
dermatomyositis (DM), and clinically amyopathic dermatomyositis (CADM); however, little is …

Purpose: To compare the performance of apparent diffusion coefficient (ADC) with that of
signal intensity of the lesion-to–spinal cord ratio (LSR) in differentiating lung cancer from …

The aim of the present study was to clarify the clinical characteristics and prognosis of
patients with interstitial lung disease (ILD) associated with amyopathic dermatomyositis (ILD-ADM)…

Objectives Myositis-specific autoantibodies (MSAs) are associated with clinical phenotypes
in polymyositis/dermatomyositis (PM/DM). No study has investigated the clinical features …

In immune cells, CD73 dephosphorylates and converts extracellular AMP into adenosine,
which binds the A2A adenosine receptor (A2AR). Blockade of this interaction, which induces …

Objectives To investigate the risk factors and prognosis associated with acute exacerbation (AE)
in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). …

Background Acute eosinophilic pneumonia (AEP) is characterized by a febrile illness, diffuse
pulmonary infiltrates, and pulmonary eosinophilia. The etiology of AEP remains unknown, …