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Decreased expression of E-cadherin and ZO-1 in the nasal mucosa of patients with allergic rhinitis: altered regulation of E-cadherin by IL-4, IL-5, and TNF-alpha
HJ Lee, B Kim, NR Im, DY Lee, HK Kim… - American journal of …, 2016 - journals.sagepub.com
Background Allergic rhinitis is a chronic nasal inflammatory disease mediated by an
immunoglobulin E mediated process to environmental allergens. Although atopy is a potent …
immunoglobulin E mediated process to environmental allergens. Although atopy is a potent …
Actin‐associated gene expression is associated with early regional metastasis of tongue cancer
DY Lee, Y Kang, NR Im, B Kim, TK Kwon… - The …, 2021 - Wiley Online Library
Objectives We aimed to analyze gene expression profile of tongue cancer associated with
early lymph node metastasis using the cancer genome atlas (TCGA) data. Study design Basic …
early lymph node metastasis using the cancer genome atlas (TCGA) data. Study design Basic …
[HTML][HTML] Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway
NR Im, B Kim, KY Jung, SK Baek - Journal of Molecular Medicine, 2022 - Springer
Laryngopharyngeal reflux disease (LPRD) is caused by pharyngeal mucosal damage due
to the reflux of gastric contents, including acid, pepsin, and bile juice. Our previous study has …
to the reflux of gastric contents, including acid, pepsin, and bile juice. Our previous study has …
[HTML][HTML] Application of M1 macrophage as a live vector in delivering nanoparticles for in vivo photothermal treatment
Introduction To enhance photothermal treatment (PTT) efficiency, a delivery method that
uses cell vector for nanoparticles (NPs) delivery has drawn attention and studied widely in …
uses cell vector for nanoparticles (NPs) delivery has drawn attention and studied widely in …
[HTML][HTML] Usefulness of matrix metalloproteinase-7 in saliva as a diagnostic biomarker for laryngopharyngeal reflux disease
NR Im, B Kim, KY Jung, SK Baek - Scientific reports, 2021 - nature.com
Several diagnostic methods are currently being used to diagnose LPRD (laryngopharyngeal
reflux disease), but have the disadvantage of being invasive, subjective, or expensive. Our …
reflux disease), but have the disadvantage of being invasive, subjective, or expensive. Our …
Effect of matrix metalloproteinase inhibitor on disrupted E‐cadherin after acid exposure in the human nasal epithelium
B Kim, HJ Lee, NR Im, DY Lee, CY Kang… - The …, 2018 - Wiley Online Library
Objective Laryngopharyngeal reflux disease (LPRD) is one of potential factors in recalcitrant
chronic rhinosinusitis with or without polyps. An increase in junctional permeability in the …
chronic rhinosinusitis with or without polyps. An increase in junctional permeability in the …
[HTML][HTML] Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5
B Kim, HJ Lee, NR Im, DY Lee, HK Kim, CY Kang… - PloS one, 2018 - journals.plos.org
Background In airway epithelium, thymus and activation-regulated chemokine (CCL17) and
macrophage-derived chemokine (CCL22) are induced by defective epithelial barriers such …
macrophage-derived chemokine (CCL22) are induced by defective epithelial barriers such …
[HTML][HTML] Role of matrix metalloproteinases 7 in the pathogenesis of laryngopharyngeal reflux: decreased E-cadherin in acid exposed primary human pharyngeal …
NR Im, DY Lee, B Kim, J Kim, KY Jung, TH Kim… - International journal of …, 2019 - mdpi.com
Cleavage of E-cadherin and the resultant weakness in the cell-cell links in the laryngeal
epithelium lining is induced by exposure to acidic contents of the refluxate. Herein, we aimed to …
epithelium lining is induced by exposure to acidic contents of the refluxate. Herein, we aimed to …
[HTML][HTML] Enhancement of aberrantly modified integrin‑mediated cell motility in multicellular tumor spheroids
B Kim, NR Im, TD Yang, J Kim… - International …, 2020 - spandidos-publications.com
Multicellular tumor spheroids (MTSs) of malignant cells can display cell‑cell and cell‑matrix
interactions, different from monolayer cultures. The objective of the present study was to …
interactions, different from monolayer cultures. The objective of the present study was to …
In vivo photothermal treatment with real-time monitoring by optical fiber-needle array
TD Yang, K Park, HJ Kim, NR Im, B Kim… - Biomedical Optics …, 2017 - opg.optica.org
Photothermal treatment (PTT) using gold nanoshells (gold-NSs) is accepted as a method for
treating cancer. However, owing to restrictions in therapeutic depth and skin damage …
treating cancer. However, owing to restrictions in therapeutic depth and skin damage …
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