Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are associated with
skeletal muscle complaints, including clinically important myositis and rhabdomyolysis, mild …

or therapeutic medical strategies. However, the ESC Guidelines do not override in any way
whatsoever the individual responsibility of health professionals to make appropriate and …

IN THE DECADE SINCE THE VITAMIN Dreceptor (VDR) was cloned (1) and recognized as
a member of the superfamily of nuclear receptors that regulate gene expression in a ligand-…

In 1995 the American College of Sports Medicine and the Centers for Disease Control and
Prevention published national guidelines on Physical Activity and Public Health. The …

Statin-associated muscle symptoms (SAMS) are one of the principal reasons for statin non-adherence
and/or discontinuation, contributing to adverse cardiovascular outcomes. This …

Regular physical activity using large muscle groups, such as walking, running, or swimming,
produces cardiovascular adaptations that increase exercise capacity, endurance, and …

Background Bempedoic acid, an ATP citrate lyase inhibitor, reduces low-density lipoprotein
(LDL) cholesterol levels and is associated with a low incidence of muscle-related adverse …

With regard to a literature search for this revision, no specific strategy or formal data quality
assessment was used. Each of the 15 members of the writing group has specific expertise in…

The role of habitual physical activity in the primary prevention of coronary heart disease (CHD)
has been reviewed by a number of qualified authors. Most recent reviews conclude that …

ContextThe effect of antihypertensive drugs on cardiovascular events in patients with coronary
artery disease (CAD) and normal blood pressure remains uncertain.ObjectiveTo compare …