Background In a randomized trial comparing mitral-valve repair with mitral-valve replacement
in patients with severe ischemic mitral regurgitation, we found no significant difference in …

Background In a trial comparing coronary-artery bypass grafting (CABG) alone with CABG
plus mitral-valve repair in patients with moderate ischemic mitral regurgitation, we found no …

Background In the era of destination continuous flow left ventricular assist devices (LVAD),
the decision of whether a patient will tolerate isolated LVAD support or will need biventricular …

Injectable hydrogels have gained popularity as a vehicle for the delivery of cells, growth
factors, and other molecules to localize and improve their retention at the injection site, as well …

Injectable hydrogels are useful for numerous biomedical applications, such as to introduce
therapeutics into tissues or for 3D printing. To expand the complexity of available injectable …

MicroRNA-based therapies that target cardiomyocyte proliferation have great potential for
the treatment of myocardial infarction. In previous work, we showed that the miR-302/367 …

Background The Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs),
a joint effort among the National Heart, Lung, and Blood Institute, the Food and Drug …

Ventricular assist device has rapidly emerged as a durable and safe therapy for end-stage
heart failure patients with >22 000 implantations to date. Though originally conceived for …

Aims Previous studies have demonstrated improved cardiac function following myocardial
infarction (MI) after administration of endothelial progenitor cells (EPCs) into ischaemic …

Background The field of mechanical circulatory support has been impacted by the approval
of new continuous-flow left ventricular assist devices (LVADs) and changes to the United …