Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

The present paper presents a hypothesis aimed at explaining why venous leg ulcers, pressure
ulcers, and diabetic foot ulcers develop into a chronic state. We propose that the lack of …

Bacteria survive in nature by forming biofilms on surfaces and probably most, if not all,
bacteria (and fungi) are capable of forming biofilms. A biofilm is a structured consortium of …

The present study was undertaken to investigate the appearance and location of Pseudomonas
aeruginosa in the cystic fibrosis (CF) lung and in sputum. Samples include preserved …

Bacteria can grow and proliferate either as single, independent cells or organized in aggregates
commonly referred to as biofilms. When bacteria succeed in forming a biofilm within the …

The opportunistic human pathogen Pseudomonas aeruginosa is the predominant micro-organism
of chronic lung infections in cystic fibrosis (CF) patients. P. aeruginosa colonizes the …

The opportunistic human pathogen Pseudomonas aeruginosa is the predominant micro-organism
of chronic lung infections in cystic fibrosis patients. P. aeruginosa colonizes the lungs …

It has become evident that aggregation or biofilm formation is an important survival
mechanism for bacteria in almost any environment. In this review, we summarize recent …

In relation to emerging multiresistant bacteria, development of antimicrobials and new
treatment strategies of infections should be expected to become a high-priority research area. …

Within recent years, it has been established that extracellular DNA is a key constituent of the
matrix of microbial biofilms. In addition, it has recently been demonstrated that DNA binds …