User profiles for Sisi Chen

Sisi Chen

- Verified email at jiangnan.edu.cn - Cited by 1176

Sisi Chen

- Verified email at mayo.edu - Cited by 1162

Sisi Chen

- Verified email at mskcc.org - Cited by 1042

[HTML][HTML] Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

S Chen, Q Wang, H Yu, ML Capitano, S Vemula… - Nature …, 2019 - nature.com
Clonal hematopoiesis of indeterminate potential (CHIP) increases with age and is associated
with increased risks of hematological malignancies. While TP53 mutations have been …

[HTML][HTML] Reconstructing aspects of human embryogenesis with pluripotent stem cells

…, V Jorgensen, BAT Weatherbee, S Chen… - Nature …, 2021 - nature.com
Understanding human development is of fundamental biological and clinical importance.
Despite its significance, mechanisms behind human embryogenesis remain largely unknown. …

[HTML][HTML] D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study

…, Q Wang, Q Shi, K Liu, Z Luo, X Chen, S Chen… - Journal of intensive …, 2020 - Springer
Background Over 5,488,000 cases of coronavirus disease-19 (COVID-19) have been reported
since December 2019. We aim to explore risk factors associated with mortality in COVID-…

[PDF][PDF] Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch

…, MR Mack, J Feng, TM Whelan, H Niu, CJ Guo, S Chen… - Cell, 2017 - cell.com
Mammals have evolved neurophysiologic reflexes, such as coughing and scratching, to
expel invading pathogens and noxious environmental stimuli. It is well established that these …

Effects of thermal hydrolysis on organic matter solubilization and anaerobic digestion of high solid sludge

Y Xue, H Liu, S Chen, N Dichtl, X Dai, N Li - Chemical Engineering Journal, 2015 - Elsevier
Anaerobic digestion of sludge not only decreases the mass/volume of sludge, but also
increases the production of energy-rich biogas. The effects of a thermal hydrolysis process (THP) …

[PDF][PDF] Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis

Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala… - Cell stem cell, 2018 - cell.com
Inflammation is a risk factor for cancer development. Individuals with preleukemic TET2
mutations manifest clonal hematopoiesis and are at a higher risk of developing leukemia. How …

[HTML][HTML] Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery

…, J Cui, L Guo, S Chen, M Jiang, L Feng, L Chen… - Nature …, 2021 - nature.com
SARS-CoV-2 vaccination has been launched worldwide to build effective population-level
immunity to curb the spread of this virus. The effectiveness and duration of protective immunity …

Economic burden of childhood overweight and obesity: A systematic review and meta‐analysis

J Ling, S Chen, NR Zahry, TSA Kao - Obesity Reviews, 2023 - Wiley Online Library
To update existing literature and fill the gap in meta‐analyses, this meta‐analysis quantitatively
evaluated the worldwide economic burden (in 2022 US $) of childhood overweight and …

[HTML][HTML] Chloranthus genome provides insights into the early diversification of angiosperms

…, R Folk, SA Smith, AS Chanderbali, S Chen… - Nature …, 2021 - nature.com
Chloranthales remain the last major mesangiosperm lineage without a nuclear genome
assembly. We therefore assemble a high-quality chromosome-level genome of Chloranthus …

[PDF][PDF] Hydrogen sulfide positively regulates abscisic acid signaling through persulfidation of SnRK2. 6 in guard cells

S Chen, H Jia, X Wang, C Shi, X Wang, P Ma, J Wang… - Molecular Plant, 2020 - cell.com
The phytohormone abscisic acid (ABA) plays pivotal roles in triggering stomatal closure and
facilitating adaptation of plants to drought stress. Hydrogen sulfide (H 2 S), a small signaling …