[HTML][HTML] Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
Clonal hematopoiesis of indeterminate potential (CHIP) increases with age and is associated
with increased risks of hematological malignancies. While TP53 mutations have been …
with increased risks of hematological malignancies. While TP53 mutations have been …
[HTML][HTML] Reconstructing aspects of human embryogenesis with pluripotent stem cells
…, V Jorgensen, BAT Weatherbee, S Chen… - Nature …, 2021 - nature.com
Understanding human development is of fundamental biological and clinical importance.
Despite its significance, mechanisms behind human embryogenesis remain largely unknown. …
Despite its significance, mechanisms behind human embryogenesis remain largely unknown. …
[HTML][HTML] D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study
…, Q Wang, Q Shi, K Liu, Z Luo, X Chen, S Chen… - Journal of intensive …, 2020 - Springer
Background Over 5,488,000 cases of coronavirus disease-19 (COVID-19) have been reported
since December 2019. We aim to explore risk factors associated with mortality in COVID-…
since December 2019. We aim to explore risk factors associated with mortality in COVID-…
[PDF][PDF] Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch
Mammals have evolved neurophysiologic reflexes, such as coughing and scratching, to
expel invading pathogens and noxious environmental stimuli. It is well established that these …
expel invading pathogens and noxious environmental stimuli. It is well established that these …
Effects of thermal hydrolysis on organic matter solubilization and anaerobic digestion of high solid sludge
Anaerobic digestion of sludge not only decreases the mass/volume of sludge, but also
increases the production of energy-rich biogas. The effects of a thermal hydrolysis process (THP) …
increases the production of energy-rich biogas. The effects of a thermal hydrolysis process (THP) …
[PDF][PDF] Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis
Inflammation is a risk factor for cancer development. Individuals with preleukemic TET2
mutations manifest clonal hematopoiesis and are at a higher risk of developing leukemia. How …
mutations manifest clonal hematopoiesis and are at a higher risk of developing leukemia. How …
[HTML][HTML] Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery
…, J Cui, L Guo, S Chen, M Jiang, L Feng, L Chen… - Nature …, 2021 - nature.com
SARS-CoV-2 vaccination has been launched worldwide to build effective population-level
immunity to curb the spread of this virus. The effectiveness and duration of protective immunity …
immunity to curb the spread of this virus. The effectiveness and duration of protective immunity …
Economic burden of childhood overweight and obesity: A systematic review and meta‐analysis
To update existing literature and fill the gap in meta‐analyses, this meta‐analysis quantitatively
evaluated the worldwide economic burden (in 2022 US $) of childhood overweight and …
evaluated the worldwide economic burden (in 2022 US $) of childhood overweight and …
[HTML][HTML] Chloranthus genome provides insights into the early diversification of angiosperms
Chloranthales remain the last major mesangiosperm lineage without a nuclear genome
assembly. We therefore assemble a high-quality chromosome-level genome of Chloranthus …
assembly. We therefore assemble a high-quality chromosome-level genome of Chloranthus …
[PDF][PDF] Hydrogen sulfide positively regulates abscisic acid signaling through persulfidation of SnRK2. 6 in guard cells
S Chen, H Jia, X Wang, C Shi, X Wang, P Ma, J Wang… - Molecular Plant, 2020 - cell.com
The phytohormone abscisic acid (ABA) plays pivotal roles in triggering stomatal closure and
facilitating adaptation of plants to drought stress. Hydrogen sulfide (H 2 S), a small signaling …
facilitating adaptation of plants to drought stress. Hydrogen sulfide (H 2 S), a small signaling …