The role of mechanical force as an important regulator of structure and function of mammalian
cells, tissues, and organs has recently been recognized. However, mechanical overload is …

Objective Preeclampsia (preE) has a significant link to alterations of placental function leading
to stress and apoptotic signaling, which pass the placental barrier and leave persistent …

Cholangiocyte proliferation is regulated in a coordinated fashion by many neuroendocrine
factors through autocrine and paracrine mechanisms. The renin-angiotensin system (RAS) is …

Background/Aim: Methylquercetin, 3,4’,7-O-trimethylquercetin (34’7TMQ), has been
reported to inhibit metastasis. Recently, we demonstrated that 34’7TMQ inhibited the in vitro …

Background: Melanoma is a malignant skin tumor and quercetin has been reported to inhibit
metastasis. A quercetin glycoside and 7 methylquercetins were synthesized from rutin to …

The purpose of this article is to review the role of different epigenetic modifications in ovarian
cancer. Epigenetic changes can lead to disease development, malignant transformation, …

Objective: Preeclampsia (preE) is a hypertensive disorder that occurs 20% in diabetic pregnancy.
We have shown that hyperglycemia impairs cytotrophoblast cell (CTB) function. In this …

Background/Aim: 3,4’,7-O-trimethylquercetin (34’7TMQ), a derivative of quercetin, inhibited
ovarian cancer cell migration and invasion without affecting proliferation. In this study, the …

Preeclampsia (preE) is a hypertensive disorder of pregnancy. Cardiotonic steroids (CTS)
are endogenous inhibitors of Na + /K + ATPase, and at least one CTS, marinobufagenin (MBG), …

… ouabain (OUB)) for 48 h. Some cells were pretreated with 10 μM p38 mitogen-activated
protein kinase (p38 MAPK) inhibitor (SB203580) for 2 h prior to CTSs treatment. We analyzed …