Rapid advances in the cancer stem cell (CSC) field have provided cause for optimism for
the development of more reliable cancer therapies in the future. Strategies aimed at efficient …

The rapid accumulation of knowledge on apoptosis regulation in the 1990s was followed by
the development of several experimental anticancer‐ and anti‐ischaemia (stroke or …

Testicular descent as a prerequisite for the production of mature spermatozoa and normal
external genitalia morphogenesis, and therefore facilitating copulation and internal fertilization…

Lipoteichoic acids (LTAs) isolated from bacterial species, including Staphylococcus aureus,
Streptococcus pyogenes A, Enterococcus faecalis, Streptococcus pneumoniae, and Listeria …

Despite advances in neurosurgical techniques and radio-/chemotherapy, the treatment of
brain tumors remains a challenge. This is particularly true for the most frequent and fatal adult …

The complex formed by two members of the S100 calcium-binding protein family, S100A8/A9,
exerts apoptosis-inducing activity in various cells of different origins. Here, we present …

Brevinin‐2R is a novel non‐hemolytic defensin that was isolated from the skin of the frog
Rana ridibunda. It exhibits preferential cytotoxicity towards malignant cells, including Jurkat (T‐…

Transforming growth factor-β 1 (TGF-β 1) is an important regulator of fibrogenesis in heart
disease. In many other cellular systems, TGF-β 1 may also induce autophagy, but a link …

The dioxin/aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor responsive
to both natural and man-made environmental compounds. AhR and its nuclear partner …

… This results in the stabilization of β-catenin, which then moves to the nucleus, forms a
compound with T cell factor/lymphocyte enhancer factor, and activates Wnt-target genes, including …