The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation

…, FE Lennon, J Siegler, T Mirzapoiazova… - Anesthesia & …, 2011 - journals.lww.com
… times, and analyzed statistically by Student t test (with statistical significance set at P < 0.05).
… Attestation: Tamara Mirzapoiazova has seen the original study data, reviewed the analysis …

Differential effects of sphingosine 1–phosphate receptors on airway and vascular barrier function in the murine lung

…, L Moreno-Vinasco, T Mirzapoiazova… - American journal of …, 2010 - atsjournals.org
The therapeutic options for ameliorating the profound vascular permeability, alveolar
flooding, and organ dysfunction that accompanies acute inflammatory lung injury (ALI) remain …

[HTML][HTML] The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung …

FE Lennon, T Mirzapoiazova, B Mambetsariev… - PloS one, 2014 - journals.plos.org
Recent epidemiologic studies implying differences in cancer recurrence based on anesthetic
regimens raise the possibility that the mu opioid receptor (MOR) can influence cancer …

[HTML][HTML] Recent Advancement in Breast Cancer Research: Insights from Model Organisms—Mouse Models to Zebrafish

…, A Mohanty, P Garg, SK Ramisetty, T Mirzapoiazova… - Cancers, 2023 - mdpi.com
Simple Summary The current article provides an overview of the significance of using various
mouse and zebrafish models in cancer research. In addition, this review discusses an …

Overexpression of the μ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis

FE Lennon, T Mirzapoiazova… - The Journal of the …, 2012 - pubs.asahq.org
Background Recent epidemiologic studies suggesting that there were differences in cancer
recurrence contingent on anesthetic regimens have raised the possibility that μ-opioid …

Increased μ-opioid receptor expression in metastatic lung cancer

PA Singleton, T Mirzapoiazova, R Hasina… - British journal of …, 2014 - academic.oup.com
Background We and others have previously demonstrated that the μ-opioid receptor (MOR)
is overexpressed in several human malignancies. There is a seven-fold increase in MOR in …

[HTML][HTML] FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells

…, R Bittman, X Lu, SM Dudek, T Mirzapoiazova… - Journal of biological …, 2009 - ASBMB
Novel immunomodulatory molecule FTY720 is a synthetic analog of myriocin, but unlike
myriocin FTY720 does not inhibit serine palmitoyltransferase. Although many of the effects of …

Essential role of pre–B-cell colony enhancing factor in ventilator-induced lung injury

…, JW Barnard, SF Ma, T Mirzapoiazova… - American journal of …, 2008 - atsjournals.org
Rationale: We previously demonstrated pre–B-cell colony enhancing factor (PBEF) as a
biomarker in sepsis and sepsis-induced acute lung injury (ALI) with genetic variants conferring …

Neuropilin-1 regulates vascular endothelial growth factor–mediated endothelial permeability

…, R Yachechko, T Mirzapoiazova… - Circulation …, 2005 - Am Heart Assoc
Neuropilin-1 (Npn-1) is a cell surface receptor that binds vascular endothelial growth factor (VEGF),
a potent mediator of endothelial permeability, chemotaxis, and proliferation. In vitro, …

[PDF][PDF] B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies

…, T Sadras, J Lee, T Mirzapoiazova, R Salgia, T Ernst… - Cell, 2018 - cell.com
B cell activation during normal immune responses and oncogenic transformation impose
increased metabolic demands on B cells and their ability to retain redox homeostasis. While …