Studies of gene function in non-model animals have been limited by the approaches available
for eliminating gene function. The CRISPR/Cas9 (clustered regularly interspaced short …

It is well accepted that Forkhead box protein L2 (Foxl2) and aromatase (Cyp19a1; the enzyme
responsible for estrogen synthesis) are critical for ovarian development in vertebrates. …

The dmrt6 gene has been isolated from tetrapods and recently from a coelacanth, Latimeria
chalumnae. Its evolutionary history and exact function remain unclear. In the present study, …

Osmotic adjustment is an important mechanism for plants to withstand osmotic stress. The
accumulation of Na + can improve the osmotic adjustment of plants and enhance the ability of …

Gonadal soma‐derived factor (gsdf) is critical for testicular differentiation in teleosts, yet
detailed analysis of Gsdf on testicular differentiation is lacking. In the present study, we knocked …

Multidrug resistance (MDR) has become a major impediment to a successful treatment for
liver cancer patients, and one of the common reasons for MDR is the activation of ABCB1 gene…

Continuous plasma separation will be greatly helpful for dynamic metabolite monitoring in
kinetics research and drug development. In this work, we proposed a continuous on-chip …

Songpu mirror carp, Cyprinus carpio L., is a new variety of common carp that has become
an economically important freshwater fish in China. However, it remains unknown how its …

Type 2 diabetes mellitus (T2DM) is a long-term metabolic disorder. It is characterized by
hyperglycemia, insulin resistance (IR), and relative impairment in insulin secretion. IR plays a …

Prediction of crop yield under water and salt stress is essential for guiding deficit irrigation in
saline soil. The responses of tomato plants to water and salt stress, and their interactions …