We report here the purification of the third protein factor, Apaf-3, that participates in caspase-3
activation in vitro. Apaf-3 was identified as a member of the caspase family, caspase-9. …

The presence of both multiple-access interference (MAI) and intersymbol interference (ISI)
constitutes a major impediment to reliable communications in multipath code-division multiple-…

A cell-free system based on cytosols of normally growing cells is established that reproduces
aspects of the apoptotic program in vitro. The apoptotic program is initiated by addition of …

The inflammatory response of mammalian cells to TNF-α can be switched to apoptosis either
by cotreatment with a protein synthesis inhibitor, cycloheximide, or Smac mimetic, a small …

Smac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a
caspase-8-activating complex containing receptor interacting protein kinase-1 (RIPK1). …

Bcl-2 is an integral membrane protein located mainly on the outer membrane of mitochondria.
Overexpression of Bcl-2 prevents cells from undergoing apoptosis in response to a variety …

We report here the purification and cDNA cloning of Apaf-1, a novel 130 kd protein from HeLa
cell cytosol that participates in the cytochrome c–dependent activation of caspase-3. The …

We have identified and purified from HeLa cytosol a protein that induces DNA fragmentation
in coincubated nuclei after it is activated by caspase-3. This protein, designated DNA …

The mRNA-cleavage step of RNA interference is mediated by an endonuclease, Argonaute2
(Ago2), within the RNA-induced silencing complex (RISC). Ago2 uses one strand of the …

Cellulose, the most abundant source of biomass, is currently regarded as a promising
alternative for fossil fuels as it cannot be digested by human beings and thus its use, unlike corn …