Functionalized carbon nanotubes: properties and applications
Carbon nanotubes can be functionalized via amidation and esterification of the nanotube-bound
carboxylic acids. The solubility of these functionalized carbon nanotubes makes it …
carboxylic acids. The solubility of these functionalized carbon nanotubes makes it …
Emerging antibody-based therapeutics against SARS-CoV-2 during the global pandemic
SARS-CoV-2 antibody therapeutics are being evaluated in clinical and preclinical stages.
As of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike …
As of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike …
Quantum dots and nanoparticles for photodynamic and radiation therapies of cancer
Semiconductor quantum dots and nanoparticles composed of metals, lipids or polymers have
emerged with promising applications for early detection and therapy of cancer. Quantum …
emerged with promising applications for early detection and therapy of cancer. Quantum …
Structure-guided discovery of a single-domain antibody agonist against human apelin receptor
…, X Song, X Ma, X Li, N Zhang, Y Song, Y Sun… - Science …, 2020 - science.org
Developing antibody agonists targeting the human apelin receptor (APJ) is a promising
therapeutic approach for the treatment of chronic heart failure. Here, we report the structure-…
therapeutic approach for the treatment of chronic heart failure. Here, we report the structure-…
Pathophysiology of acute graft-versus-host disease: recent advances
Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for
many malignant and nonmalignant hematologic diseases. Donor T cells from the allografts …
many malignant and nonmalignant hematologic diseases. Donor T cells from the allografts …
GVHD pathophysiology: is acute different from chronic?
Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic
cell transplantation (HCT). GVHD occurs in acute and chronic forms. Acute GVHD usually …
cell transplantation (HCT). GVHD occurs in acute and chronic forms. Acute GVHD usually …
Gut microbiome–derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease
…, T Toubai, K Oravecz-Wilson, SR Wu, Y Sun… - Nature …, 2016 - nature.com
The effect of alterations in intestinal microbiota on microbial metabolites and on disease
processes such as graft-versus-host disease (GVHD) is not known. Here we carried out an …
processes such as graft-versus-host disease (GVHD) is not known. Here we carried out an …
[HTML][HTML] Histone deacetylase inhibition modulates indoleamine 2, 3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in …
Histone deacetylase (HDAC) inhibitors are antitumor agents that also have antiinflammatory
properties. However, the mechanisms of their immunomodulatory functions are not known. …
properties. However, the mechanisms of their immunomodulatory functions are not known. …
[HTML][HTML] RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis
…, S Beach, S Mott, R Roy, C Braastad, Y Sun… - Journal of Biological …, 2004 - ASBMB
Cancer cells are more susceptible to chemotherapeutic agent-induced apoptosis than their
normal counterparts. Although it has been demonstrated that the increased sensitivity results …
normal counterparts. Although it has been demonstrated that the increased sensitivity results …
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
PTEN-induced putative kinase 1 (PINK1) and Parkin act in a common pathway to regulate
mitochondrial dynamics, the involvement of which in the pathogenesis of Parkinson's disease (…
mitochondrial dynamics, the involvement of which in the pathogenesis of Parkinson's disease (…