Importance The US is currently an epicenter of the coronavirus disease 2019 (COVID-19)
pandemic, yet few national data are available on patient characteristics, treatment, and …

… All three Ewing’s sarcoma cell lines screened showed both high SLFN11 expression and
sensitivity to irinotecan (Fig. 4b and Supplementary Fig. 14). Ewing’s sarcomas also exhibited …

Extensive experimental data from high-energy nucleus-nucleus collisions were recorded
using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive …

Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links between …

Extensive research during the past 2 decades has revealed the mechanism by which
continued oxidative stress can lead to chronic inflammation, which in turn could mediate most …

Sustainability indicators and composite index are gaining lot of importance and increasingly
recognized as a powerful tool for policy making and public communication in providing …

The Cancer Genome Atlas Network recently cataloged recurrent genomic abnormalities in
glioblastoma multiforme (GBM). We describe a robust gene expression-based molecular …

Background Data on patients with COVID-19 who have cancer are lacking. Here we characterise
the outcomes of a cohort of patients with cancer and COVID-19 and identify potential …

Background Cabazitaxel is a novel tubulin-binding taxane drug with antitumour activity in
docetaxel-resistant cancers. We aimed to compare the efficacy and safety of cabazitaxel plus …

Protein kinases activated by dual phosphorylation on Tyr and Thr (MAP kinases) can be
grouped into two major classes: ERK and JNK. The ERK group regulates multiple targets in …