Purpose: Applications are being sought to identify novel genes which interact with specific environmental exposures to modify risk factors for heart, lung, blood, and sleep (HLBS) disorders. The genetic aspects of response to environmental change, and related biological mechanisms, will be studied using short term, focused interventions in families. The goal of this Request for Applications (RFA) is to identify subgroups based on genotype who are most likely to benefit from targeted environmental changes designed to reduce the development or progression of HLBS diseases.
Term/Amount: The NHLBI intends to commit approximately $9,000,000 in FY 2002 to fund 3 to 5 new grants in response to this RFA. Up to $36,000,000 (total cost) over the entire project period is available to support this initiative. Because the nature and scope of the research proposed may vary, it is anticipated that the size of each award will also vary. Although the financial plans of the NHLBI provide support for this program, awards pursuant to this RFA are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications. At this time, there is no plan to reissue this RFA.
Contact: The letter of intent is to be sent to Deborah Beebe, Ph.D. Division of Extramural Affairs National Heart, Lung, and Blood Institute 6701 Rockledge Drive, Room 7178, MSC 7924 Bethesda, MD 20892-7924 Telephone: (301) 435-0270 FAX: (301) 480-3541 Email: beebed{at}nhlbi.nih.gov The PHS 398 research grant application instructions and forms (rev. 5/2001) at http://grants.nih.gov/grants/funding/phs398/phs398.html are to be used in applying for these grants. This version of the PHS 398 is available in an interactive, searchable PDF format. Beginning January 10, 2002, the NIH will return applications that are not submitted on the 5/2001 version. For further assistance contact GrantsInfo, Telephone 301/435-0714, Email: GrantsInfo{at}nih.gov.
Deadline: Letter of Intent Receipt Date: February 20, 2002. Application Receipt Date: March 22, 2002.